Study of lipid profile in streptozotocin (stz) – induced diabetic rats under nicotinamide coverage treated with ocimum gratissimum (o.g.) and vernonia amygdalina (v.a.)

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Lipid Profile Overview
  • 2.2Diabetes Mellitus and Lipid Profile
  • 2.3Streptozotocin (STZ) Induced Diabetes
  • 2.4Nicotinamide Coverage in Diabetes Treatment
  • 2.5Ocimum Gratissimum (O.G.) in Diabetes Management
  • 2.6Vernonia Amygdalina (V.A.) in Diabetes Management
  • 2.7Experimental Studies on Lipid Profile
  • 2.8Effects of Medicinal Plants on Lipid Profile
  • 2.9Role of Diet in Lipid Profile Management
  • 2.10Current Research Trends in Lipid Profile Studies

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Methodology Overview
  • 3.2Research Design and Approach
  • 3.3Selection of Sample Population
  • 3.4Data Collection Methods
  • 3.5Data Analysis Techniques
  • 3.6Ethical Considerations
  • 3.7Reliability and Validity of Data
  • 3.8Limitations of the Research Methodology

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Analysis of Lipid Profile Data
  • 4.2Impact of STZ Induction on Lipid Profile
  • 4.3Effects of Nicotinamide Coverage on Lipid Profile
  • 4.4Evaluation of O.G. Treatment on Lipid Profile
  • 4.5Assessment of V.A. Treatment on Lipid Profile
  • 4.6Comparison of Medicinal Plants' Effects on Lipid Profile
  • 4.7Discussion on Lipid Profile Changes
  • 4.8Implications for Diabetes Management

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Conclusion and Summary
  • 5.2Recap of Research Objectives
  • 5.3Key Findings Overview
  • 5.4Contributions to Existing Knowledge
  • 5.5Practical Implications
  • 5.6Recommendations for Future Research

Project Abstract

<p> The effect of leaf extract of ocimum gratissimium (scent leaf) and vernonia Amygdalina (bitter leaf) under nicotinanmide coverage was studied using albino wistar rat. Acute toxicity of the plant was carried out using (Lorkes method). LD50 was calculated to be 208 mglkg. The main work involved 49 albino wistar rats weighing 150g to 200g. The rats were put in 7 groups of 7 rats each. Rats in group I served as the control and were administered distilled water and feed. Rats in Groups II-VII were administered OG, V.A, DM+NICO, DM+NICO+OG, DM+NICO+VA, DM+NICO+OG+VA respectively for 28 days according to their body weight. Oral administration was used for all the groups. The result obtained showed the mean± SEM P values (P&lt;0.05) was taken as significant. DM + NICO + OG lowered (P&lt;0.05) the VLDL level. DM + NICO + VA lowered (P&lt;0.05) T – CHOL level compared to the control but DM + NICO + VA was seen to raise T-CHOL level. DM + NICO + OG +V.A significantly lowered (P&lt;0.05) the TG level compared to control, O.G and DM + NICO + VA + O.G groups. According to the study, NICO + V.A lowers Lipid profile. O.G increases LDL levels thereby increasing the risk of atherosclerosis and cardiovascular complication. <br></p>

Project Overview

Blazingprojects Mobile App

📚 Over 50,000 Project Materials
📱 100% Offline: No internet needed
📝 Over 98 Departments
🔍 Software coding and Machine construction
🎓 Postgraduate/Undergraduate Research works
📥 Instant Whatsapp/Email Delivery

Blazingprojects App

Related Research

Microbiology. 2 min read

Exploration of Antimicrobial Resistance Patterns in Clinical Bacterial Isolates from...

What This Project Is About This project looks at bacteria collected from hospitals in urban areas to understand how they resist the medicines meant to kill them...

BP
Blazingprojects
Read more →
Microbiology. 2 min read

Assessment of Antimicrobial Resistance Patterns in Clinical Isolates of Multidrug-Re...

What This Project Is About This project looks into dangerous bacteria found in hospitals and clinics that do not respond to common medicines called antibiotics....

BP
Blazingprojects
Read more →
Microbiology. 2 min read

Development of a Rapid Diagnostic Test for Multidrug-Resistant Tuberculosis Using CR...

What This Project Is About This project focuses on developing a new test to quickly identify if a person has tuberculosis (TB) that is resistant to common drugs...

BP
Blazingprojects
Read more →
Microbiology. 3 min read

Development of Rapid Diagnostic Techniques for Antibiotic-Resistant Bacterial Strain...

This project is about creating faster ways to identify bacteria that are resistant to antibiotics in medical labs. Normally, when patients get infections, docto...

BP
Blazingprojects
Read more →
Microbiology. 4 min read

Investigating Antimicrobial Resistance Patterns in Clinical Isolates of Multidrug-Re...

This project is about studying bacteria that cause infections in hospitals and other healthcare settings, specifically focusing on bacteria that are resistant t...

BP
Blazingprojects
Read more →
Microbiology. 2 min read

Investigation of the antimicrobial potential of plant extracts against drug-resistan...

The project titled &quot;Investigation of the antimicrobial potential of plant extracts against drug-resistant bacteria&quot; aims to explore the effectiveness ...

BP
Blazingprojects
Read more →
Microbiology. 4 min read

Study of the Antimicrobial Activity of Natural Plant Extracts Against Pathogenic Bac...

The project titled &quot;Study of the Antimicrobial Activity of Natural Plant Extracts Against Pathogenic Bacteria&quot; aims to investigate and evaluate the po...

BP
Blazingprojects
Read more →
Microbiology. 3 min read

Exploring the Antimicrobial Activities of Plant Extracts Against Drug-Resistant Bact...

The research project titled &quot;Exploring the Antimicrobial Activities of Plant Extracts Against Drug-Resistant Bacteria&quot; aims to investigate the potenti...

BP
Blazingprojects
Read more →
Microbiology. 3 min read

Investigation of the antimicrobial properties of plant extracts against drug-resista...

The project titled &quot;Investigation of the antimicrobial properties of plant extracts against drug-resistant bacteria&quot; aims to explore the potential of ...

BP
Blazingprojects
Read more →
WhatsApp Click here to chat with us