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Biochemistry
Showing 1-30 of 1,127 projects
Development of a CRISPR-based biosensor for rapid detection of antibiotic resistance...
The rapid and accurate detection of antibiotic resistance genes (ARGs) is a critical driver in guiding effective antimicrobial therapy and surveillance of resis...
Engineering of enzymatic cascades for selective biomass-derived chemical synthesis: ...
This study advances the engineering of enzymatic cascades to enable selective conversion of biomass-derived substrates into value-added chemicals through well-o...
Development of a CRISPR-based diagnostic platform for rapid detection of antimicrobi...
This study reports the development and validation of a CRISPR-based diagnostic platform that enables rapid, sensitive, and specific detection of antimicrobial r...
Development and optimization of CRISPR-based STRIP-tag system for real-time visualiz...
This study presents the development and optimization of a CRISPR-based STRIP-tag system designed for real-time visualization of lipid metabolism enzymes in live...
Characterization of novel plant-derived polyphenols as modulators of mitochondrial b...
Mitochondrial dysfunction and metabolic rewiring are hallmark features of cancer cells, presenting a unique therapeutic window for targeting bioenergetic pathwa...
Design, synthesis, and functional characterization of a novel biosynthetic pathway f...
This study reports the design, synthesis, and functional characterization of a novel biosynthetic pathway engineered into Escherichia coli to enhance production...
Development of a label-free, rapid biosensor for early detection of metabolic syndro...
The global burden of metabolic syndrome (MetS) necessitates rapid, accurate, and cost-effective diagnostic tools for early intervention. This study presents a l...
Characterization of plant-based polyphenolic proteins and their role in modulating o...
Characterization of plant-based polyphenolic proteins and their role in modulating oxidative stress in human cellular models investigates the intersection of pl...
Metabolomic profiling of sacaride-conjugated bile acids in non-alcoholic fatty liver...
Metabolomic profiling of sacaride-conjugated bile acids in non-alcoholic fatty liver disease (NAFLD) using UHPLC-MS/MS provides a comprehensive, high-resolution...
Optimization of CRISPR-based metabolic pathway engineering for enhanced biosynthesis...
CRISPR-based metabolic pathway engineering offers a transformative approach to enhance the biosynthesis of high-value bioproducts in Saccharomyces cerevisiae by...
Smartphone-based colorimetric sensing platform for on-site detection of microbial co...
The escalating threat of microbial contamination and adulteration in food necessitates rapid, cost-effective, and portable analytical methods capable of deliver...
Optimization of a CRISPR-based metabolic pathway engineering in Saccharomyces cerevi...
Optimization of a CRISPR-based metabolic pathway engineering in Saccharomyces cerevisiae for enhanced biosynthesis of a high-value bioproduct presents a systema...
Characterization of plasma membrane-associated lipid rafts in neurodegenerative dise...
Lipid rafts within plasma membranes are dynamic, cholesterol-rich microdomains that organize signaling networks and trafficking pathways, and their perturbation...
Exploring the Role of Microbiome-Derived Metabolites in Modulating Human Immune Cell...
Microbiome-derived metabolites have emerged as pivotal mediators linking dietary inputs to host immune regulation, yet how nutrient variability shapes these int...
Optimization and characterization of a novel multicopper oxidase for enhanced biorem...
The study presents a comprehensive investigation into a novel multicopper oxidase (MCO) with enhanced bioremediation capabilities for organic pollutants across ...
Engineering a label-free electrochemical immunoassay for rapid quantification of fas...
The development of a rapid, label-free electrochemical immunoassay leveraging graphene-based aptamer sensors offers a transformative approach for quantifying fa...
Development and optimization of CRISPR-based epigenetic editing to modulate gene exp...
CRISPR-based epigenetic editing offers a precise modality to alter gene expression without changing the underlying DNA sequence, presenting a transformative app...
Optimization of a CRISPR-based metabolic pathway for enhanced biosynthesis of a high...
Optimization of a CRISPR-based metabolic pathway in a cyanobacterial chassis to enhance biosynthesis of a high-value bioproduct is demonstrated through a system...
Engineering a microalgal system for bioactive lipid production under varying light a...
This study investigates the optimization of bioactive lipid production in a microalgal system under controlled variations in light intensity, photoperiods, and ...
Development of a CRISPR-based diagnostic platform for rapid detection of antibiotic ...
The rapid and accurate identification of antibiotic resistance genes (ARGs) in clinical bacterial isolates is critical for timely and appropriate antimicrobial ...
Design and evaluation of a green fluorescent protein-based Förster resonance energy...
Real-time monitoring of cellular redox dynamics is essential for understanding oxidative stress responses, metabolic regulation, and signaling pathways in live ...
Development of a Novel Biosensor for Rapid Detection of Antibiotic Resistance Genes ...
The rapid and accurate detection of antibiotic resistance genes in pathogenic bacteria is crucial for effective clinical decision-making and public health manag...
Development of a Novel Enzymatic Biosensor for Rapid Detection of Antibiotic Residue...
The increasing prevalence of antibiotic residues in food products poses significant health risks to consumers and challenges to food safety regulation, necessit...
Design and Characterization of Novel Enzyme Inhibitors for Targeted Cancer Therapy...
The continual emergence of resistance to conventional chemotherapeutic agents and the nonspecific toxicity associated with current cancer treatments necessitate...
Design and optimization of enzyme-based biosensors for rapid glucose detection...
The rapid and accurate detection of glucose levels is paramount for effective management of diabetes mellitus, necessitating the development of reliable biosens...
Development of Nanoparticle-Based Drug Delivery Systems for Targeted Cancer Therapy...
Cancer remains one of the leading causes of mortality worldwide, with conventional chemotherapy often associated with significant systemic toxicity, drug resist...
Design and optimization of enzymatic biosensors for rapid detection of environmental...
The increasing prevalence of environmental pollutants such as heavy metals, pesticides, and industrial chemicals poses a significant threat to ecosystems and hu...
Designing Enzyme-based Biosensors for Rapid Detection of Neurodegenerative Disease B...
The development of rapid, accurate, and cost-effective diagnostic tools for neurodegenerative diseases is a pressing need in modern medicine, given the increasi...
Optimization of Enzyme Immobilization Techniques for Enhanced Biosensor Performance...
The performance of biosensors heavily depends on the efficiency and stability of enzyme immobilization techniques, which impact their sensitivity, specificity, ...
Development of a Novel Enzymatic Assay for Rapid Detection of Oxidative Stress Marke...
Oxidative stress is a critical factor implicated in the pathogenesis of numerous diseases, including cancer, cardiovascular disorders, neurodegenerative disease...
