Antibiotics resistance profile of escherichia coli isolated from apparently healthy domestic livestock

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Antibiotics Resistance
  • 2.2Escherichia coli in Domestic Livestock
  • 2.3Antibiotics Usage in Livestock Farming
  • 2.4Resistance Mechanisms in Escherichia coli
  • 2.5Global Impact of Antibiotics Resistance
  • 2.6Studies on Antibiotics Resistance in Livestock
  • 2.7Factors Contributing to Antibiotics Resistance
  • 2.8Strategies to Combat Antibiotics Resistance
  • 2.9Role of Veterinary Medicine in Antibiotics Use
  • 2.10Future Perspectives on Antibiotics Resistance

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Sampling Techniques
  • 3.3Data Collection Methods
  • 3.4Data Analysis Procedures
  • 3.5Ethical Considerations
  • 3.6Validity and Reliability
  • 3.7Research Limitations
  • 3.8Research Assumptions

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Overview of Research Findings
  • 4.2Antibiotics Resistance Profile in Domestic Livestock
  • 4.3Distribution of Escherichia coli Strains
  • 4.4Factors Influencing Resistance Patterns
  • 4.5Comparison with Previous Studies
  • 4.6Discussion on Resistance Mechanisms
  • 4.7Implications for Livestock Health
  • 4.8Recommendations for Future Research

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Conclusion and Summary
  • 5.2Summary of Findings
  • 5.3Contributions to the Field
  • 5.4Practical Implications
  • 5.5Recommendations for Practice
  • 5.6Areas for Future Research

Project Abstract

<p> <em>This study was conducted to determine the antibiotic resistance profile of Escherichial Coli isolate from apparently healthy domestic livestock viz cow, goats and chicken from Osun State Nigeria. E. Coli was isolated using Eosin methylene Blue Agar (EMB) and identified by conventional microbiological technique. The isolate were tested against 14 antibiotics using the disc diffusion method. A total of 42 different antibiotics resistance profile were observed with each isolate showing resistance to at least four or more drugs tested. Generally, the E. coli isolates showed resistance rates of 93.8% to Ampicilin; 15.3% to Chloramphenicol, 52.7% to cloxacillin, 74.3% Erythromycin, 20.9% to Gentamicin, 53.8% to Penicillin, 17.7% to Streptomycin, 67.3% to Tetracyclin, 21.1% to Ceftazidine 70.7% to Cefuroxine, 20.5% to Cefixine, 28.8% to Ofloxacine, 58.6% to Augmentin, 27.2% to Nitorfurantion 27.3% to Ciprofloxacin. Statistical analysis showed that average number of resistance phenotypes per isolate was significantly higher for cow compared with poultry. A significant public health concern observed in this study is that multi drug resistant commensal E. Coli strains may constitute a potential reservoir of resistance genes that could be transferred to pathogenic bacteria. &nbsp; &nbsp;</em> <br></p>

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