Prevalence of hiv/aids among intending donors

Project Abstract

The prevalence of HIV/AIDS among intending blood donors is a critical issue that has significant implications for blood transfusion safety worldwide. This research project aims to investigate the prevalence of HIV/AIDS among intending donors in order to assess the potential risks associated with blood donation and develop strategies to mitigate these risks. The study will involve a comprehensive review of existing literature on the subject, as well as the collection and analysis of data from blood donation centers and healthcare facilities. The research will focus on identifying the demographic characteristics of intending donors who are at a higher risk of HIV/AIDS, including factors such as age, gender, and socio-economic status. By understanding the profile of individuals who may be more likely to have HIV/AIDS, blood donation centers can target interventions and educational campaigns more effectively to prevent the transmission of the virus through blood transfusions. In addition to demographic factors, the study will also explore behavioral risk factors that may contribute to the prevalence of HIV/AIDS among intending donors. This may include factors such as sexual behavior, injection drug use, and previous exposure to contaminated blood products. By identifying these risk factors, blood donation centers can implement screening protocols to identify individuals who may be at a higher risk of HIV/AIDS and prevent them from donating blood. The research will also assess the effectiveness of current screening procedures for HIV/AIDS among intending donors and identify areas for improvement. This may include evaluating the accuracy of current testing methods, the frequency of testing, and the training of staff at blood donation centers. By improving the screening process, blood donation centers can enhance the safety of the blood supply and reduce the risk of transmitting HIV/AIDS through transfusions. Overall, this research project will provide valuable insights into the prevalence of HIV/AIDS among intending donors and inform strategies to enhance blood transfusion safety. By understanding the demographic and behavioral risk factors associated with HIV/AIDS, blood donation centers can implement targeted interventions to prevent the transmission of the virus and ensure the safety of the blood supply for all recipients.

Project Overview

<p> </p><p>INTRODUCTION</p><p>Laboratory testing to identify HIV infection has been used throughout the world for over 20 years, and continues to be a major intervention in protecting recipients of blood and tissues (Constantine et al., 2005). Serological screening of donor blood for HIV antibodies remains a critical component in identifying and eliminating HIV infected blood donations (Nkengasong et al., 1999) but, this test rarely detect HIV antigen positive blood donors who are in the window period.</p><p>Detection of this early viraemic stage continues to be a challenge in transfusion medicine worldwide because of the possibility of transmitting HIV infection (Polywka et al., 2005). Many countries employ stringent blood donor selection criteria to defer potentially infectious donors with high risk of HIV infection and employ highly sensitive screening methods like Nucleic Acid Amplification Testing (NAAT) in a nationally coordinated Blood Transfusion Service. Following this approach, developed countries like the United States of America (USA), United Kingdom (UK) and France have successfully reduced infections through their blood supplies and the window period from an average of 22 days based on antibody ELISA to 11days using NAAT (Busch et al., 2003). In Africa where about 5 to 10% of cases of HIV are reported to have been acquired through blood transfusion (WHO, 2002), the use of sensitive testing assays has persistently posed a daunting challenge for most nations.</p><p>In Nigeria, the national prevalence of HIV among blood donors was reported to be 4.4% (PEPFAR, 2006) though, different researchers (Irene, 2002; Durosinmi et al., 2003; Imoru et al., 2003; Ejele et al., 2005) have reported varying prevalence from different parts of Nigeria depending on the setting, nature of blood donation, population prevalence, donor selection criteria and methods of assays employed in testing. Pre-transfusion screening of blood is aimed at reducing to the barest minimum the acquisition of transfusion transmissible infections like HIV through donated blood. Facilities for early detection of infection with newer technologies in asymptomatic carriers thereby narrowing the window period are not available in the study setting. Screening of blood donors rely on available antibody-based detection method for HIV infection. Local data from this centre on the percentage of post transfusion acquired HIV infection are lacking as far as the authors are aware.</p><p>1.2 Problem Statement</p><p>Detection of the early viraemic stage of HIV continues to be a challenge in transfusion medicine worldwide because of the possibility of transmitting HIV infection. Serelogical screening of donor blood for HIV antibodies remains a critical component of identifying and eliminating HIV infected blood donations but this test rarely detect HIV antigen positive blood donors who are in the window period. Hence there is need to assess the prevalence of HIV/AIDS among intending donors.</p><p>1.3 Objectives of the Study</p><p>The major objective of the study is the prevalence of HIV/AIDS among intending donors.</p><p>1.4 Research Questions</p><p>(1) what is HIV/AIDS?</p><p>(2) what are its mode of transmission?</p><p>(3) what is its prevalence in the population?</p><p>(4) why the need to know its prevalence among intending donors?</p><p>1.5 Significance of the Study</p><p>This study gives a clear insight into the prevalence of HIV/AIDS among intending donors. It also serves part of a preliminary study to identify intending blood donors that are medically fit to donate blood.</p><p>1.6 Scope of the study</p><p>The research focuses on the prevalence of HIV/AIDS among intending donors.</p><p>REFERENCES</p><p>Baah ATD, Azumah DE, Ampiah C, Boampong J, Nuvor SV (2014). Incidence of human immunodeficiency virus in sickle cell patients in the Cape Coast Metropolis, Ghana. World J. 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