EPIDEMIOLOGICAL STUDIES AND MOLECULAR CHARACTERISATION OF DERMATOPHYTES AMONG ALMAJIRAI IN MAKARFI LOCAL GOVERNMENT AREA OF KADUNA STATE

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Dermatophytes
  • 2.2Epidemiological Studies on Dermatophytes
  • 2.3Molecular Characterization Techniques
  • 2.4Almajirai Community in Nigeria
  • 2.5Dermatophyte Infections among Almajirai
  • 2.6Socioeconomic Factors Influencing Dermatophyte Transmission
  • 2.7Treatment and Control of Dermatophyte Infections
  • 2.8Global Perspectives on Dermatophyte Research
  • 2.9Emerging Trends in Dermatophyte Studies
  • 2.10Gaps in Current Literature

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design and Approach
  • 3.2Sampling Techniques
  • 3.3Data Collection Methods
  • 3.4Data Analysis Procedures
  • 3.5Ethical Considerations
  • 3.6Reliability and Validity
  • 3.7Research Limitations
  • 3.8Study Variables and Measurements

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Demographic Characteristics of Almajirai Participants
  • 4.2Prevalence of Dermatophyte Infections
  • 4.3Molecular Identification of Dermatophytes
  • 4.4Risk Factors for Dermatophyte Transmission
  • 4.5Treatment Patterns among Almajirai
  • 4.6Comparison with General Population
  • 4.7Discussion on Socioeconomic Impact
  • 4.8Recommendations for Future Interventions

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusions
  • 5.3Implications for Public Health
  • 5.4Recommendations for Policy and Practice
  • 5.5Areas for Future Research

Project Abstract

<p> </p><p><strong>A</strong><strong>B</strong><strong>S</strong><strong>T</strong><strong>R</strong><strong>A</strong><strong>C</strong><strong>T</strong></p><p>This study is undertaken to measure the variation of terrestrial gamma radiation and the</p><p>activity concentrations of U-238, Th-232 and K-40 in soil of Northern part of Zamfara State (Nigeria), and assess the potential health hazards associated with the exposures to the natural radiation in the area with respect to geological formations. Inspector AlertTM Nuclear Radiation Monitor and HPGe gamma ray spectrometer were used for TGRD and laboratory analyses respectively. The measured TGRD rates ranged from 20.00 to 61.43 nGy/h, with mean value of 31.99 nGy/h. The mean (range) activity concentrations of U-238, Th-232 and K-40 in the soil samples were 19.43 ± 2.23 (8.82 ± 0.95 to 44.22 ± 5.78) Bq/kg, 23.26 ± 8.43 (11.02 ± 1.03 to 43.96 ± 2.15) Bq/kg and 268.62 ± 39.03 (57.45 ± 2.88 to 527.36 ± 12.38) Bq/kg respectively. These results were compared with the world average values for specific activities (i.e. 33, 45 and 420 Bq/kg) for U-238, Th-232 and K-40 respectively, and were found to be less than the worldwide average. The highest TGRD rate and activity concentrations of U-238, Th-232 and K-40 were recorded in an area underlain by Older Granite formation, which are enriched with high contents of radioactive materials. The radiological hazards to the public in the studied area was assessed by estimating mean values of radium equivalent activity, external hazard index, and activity utilization index for the soil samples were found to be 71.674± 7.099 Bq/kg, 0.1936± 0.0192, and 0.4688± 0.0448 respectively.In addition, the mean values of absorbed gamma dose rates, annual outdoors effective dose rates, and excess lifetime cancer risk for both TGRD rate measurements and spectrometric analyses were found to be 31.99 nGy/h, 0.0393 mSv/y and 137.6x10-6, and 33.467</p><br> <br><p></p>

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