Effect of telferia occidentalis and vernonia amygdalina on lipid profile (total cholesterol, triglyceride, hdl and ldl) on brain, plasma and kidney in high sucrose diet fed rats

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Lipid Profile
  • 2.2Importance of Total Cholesterol
  • 2.3Role of Triglycerides in the Body
  • 2.4Functions of HDL Cholesterol
  • 2.5Impact of LDL Cholesterol on Health
  • 2.6Telferia Occidentalis in Traditional Medicine
  • 2.7Vernonia Amygdalina in Ethnomedicine
  • 2.8Effects of High Sucrose Diet on Rats
  • 2.9Interaction of Telferia Occidentalis and Vernonia Amygdalina
  • 2.10Previous Studies on Lipid Profile and Herbal Interventions

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Methodology Overview
  • 3.2Selection of Animal Model
  • 3.3Preparation of High Sucrose Diet
  • 3.4Administration of Telferia Occidentalis and Vernonia Amygdalina
  • 3.5Collection of Brain, Plasma, and Kidney Samples
  • 3.6Analysis of Lipid Profile Parameters
  • 3.7Statistical Analysis Plan
  • 3.8Ethical Considerations in Animal Research

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Lipid Profile Results in Brain Samples
  • 4.2Lipid Profile Results in Plasma Samples
  • 4.3Lipid Profile Results in Kidney Samples
  • 4.4Comparison of Telferia Occidentalis and Vernonia Amygdalina Effects
  • 4.5Discussion on Mechanisms of Action
  • 4.6Impact of Herbal Interventions on Total Cholesterol
  • 4.7Influence on Triglyceride Levels
  • 4.8Implications for HDL and LDL Cholesterol

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusions Drawn from the Study
  • 5.3Contributions to Existing Knowledge
  • 5.4Recommendations for Future Research
  • 5.5Practical Applications of the Study

Project Abstract

<p> Sixty (60) albino rats of the wistar strain were used to investigate the effect different vegetables extracts modified diets; shared into two groups, one part fed with high sucrose diet while others were fed with normal ratchow. Lipid profile status were analysed in the plasma, brain and kidney after four weeks of feeding. The brain revealed a significant (p&lt;0.05) decrease in triglycer <br></p>

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