Cardio protective activities of n-hexane extract of desmodium velutinum stem on albino wister rat

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of study
  • 1.3Problem Statement
  • 1.4Objective of study
  • 1.5Limitation of study
  • 1.6Scope of study
  • 1.7Significance of study
  • 1.8Structure of the research
  • 1.9Definition of terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Cardiovascular Diseases
  • 2.2Desmodium Velutinum and its Medicinal Properties
  • 2.3Previous Studies on Cardio Protective Activities
  • 2.4Mechanisms of Cardio Protection
  • 2.5Extraction Methods for N-Hexane Extract
  • 2.6Chemical Composition of Desmodium Velutinum Stem
  • 2.7Animal Models Used in Cardio Protection Studies
  • 2.8Evaluation of Cardio Protective Activities
  • 2.9Challenges in Cardio Protection Research
  • 2.10Future Directions in Cardio Protection Research

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design and Justification
  • 3.2Selection of Study Participants
  • 3.3Data Collection Methods
  • 3.4Experimental Protocol
  • 3.5Data Analysis Techniques
  • 3.6Ethical Considerations
  • 3.7Measurement of Cardio Protective Parameters
  • 3.8Statistical Analysis Plan

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Overview of Research Findings
  • 4.2Effects of N-Hexane Extract on Cardiac Function
  • 4.3Impact on Blood Pressure and Lipid Profile
  • 4.4Histological Examination of Cardiac Tissues
  • 4.5Comparison with Standard Drugs
  • 4.6Time-Dependent Effects
  • 4.7Gender-Based Differences
  • 4.8Adverse Effects and Safety Profile

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusion
  • 5.3Implications for Clinical Practice
  • 5.4Recommendations for Future Research
  • 5.5Contribution of the Study to Cardio Protection Science

Project Abstract

<p> This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four wre fed with the aid of a syringe without needle with 6ml of the lipoprotein food mixture containing 3.6g of the cow’s brain twice a day for seven days. Rats on group two was fed with only grower’s mash and water for seven days; rats in group three was later administered orally 2ml of dissolved vasoprin drug once in a day for 3 days. Rats in group four were also administered orally 0.5ml of the liquid drug extract of Desmodium Velutinum stem once a day for 3 days. During these three (3) days, the rats were given grower’s mash and water. After the feeding period, the rate fed with the cow’s brain showed a significant increases in the activities of marker enzymes such as creatine kinase (CK), creatine kinase MB (CKMB), Aspartatatranseaminase (AST), Alaninetransminase (ALT), and lactatedehydrogenase. This study shows that N-hexane extract of Desmodium Velutinum stem posses cardio protective effect on albino wister rats than the known drug (vasoprin) if only one can increase the dosage of the extract for a period of time. <br></p>

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