The effect of pterocarpus mildbreadii seed on plasma hdl cholesterol of albino rat

Project Abstract

<p> This work was carried out to investigate the effects of pterocarpus mildbreadii<br>seed on the HDL- level of albino rats.High density lipoprotein(HDL) is a fraction<br>of cholesterol,which helps to transport cholesterol from peripheral of cell to<br>the liver.High density lipoprotein is carried out to investigate cardio vascular<br>diseases.Fresh oha seed (pterocarpus mildbreadii seed) was collected from<br>Amokwe in udi local government Area Enugu state. They were dried at room<br>temperature for about a month in an open laboratory space, groud into coarse<br>form and weighed on an electrical weighing balance. 3% tween-80 was<br>prepared by dissolving 3% tween -80 in 97ml of distilled water. The grounded<br>pterocarpus mildbreadii was dissolve in the 3% tween-80.A total of sixteen<br>wistar abino rats used for this analysis. The rats were divided into 4(four)<br>groups. Group 1contain 4 rats and received 0.5 each of 3% tween-80. Group 2<br>contain 5 rats and were administered with 1400mg/kg b.w of pteridocarpus<br>mildreadii solution Group 3 contain 3 rats and were administered with<br>2600mg/kg. b.w of pteridocarpus mildbreadii solution. Group 4 contain 4 rats<br>and were administered with 500mg/kg. b.w. of Edmard MRT complex. <br></p>

Project Overview

<p> INTRODUCTION<br>1.0 Pterocarpus mildbreadii are trees with edible parts successfully<br>budded, pterocarpus species (P.Soyauxii and P. mildbeadii are reported to<br>have different patterns of leaf flush, one spontanous and the other<br>intermitted making the first suitable for commercial production and the<br>second the home production (Okafor 1978). Pterocarpus mildbreadii<br>being the major case study both the vegetable and the seeds.<br>The vegetable is majorly used in our various home for cooking.<br>Pterocarpus mildbreadii (Oha seed) are not consumed by the people<br>from the eastern part of Nigeria. So it cannot be majorly stated the<br>content of this oha seed.<br>The demand for vegetable oils as a result of diminishing source of<br>oils and fats creates the needs for new sources as well as exploiting<br>sources that are currently unexploited in order to supplement the existing<br>ones (Minzangi et al. 2011).<br>As industrialists continues to rely mostly on the popular vegetable<br>oil like coconut oil, soyabeans oil, ground nut oil, palm oil etc. for the<br>preparation and production of their various products.<br>10<br>Plant lipids also posses nutritive value and have an impact on<br>human nutrition and the world economy.more than three quarters of the<br>edible and industrial oils marketed annually are derived from seed and<br>fruit triglycerol (Schimid &amp; Ohlrogge, 2002). Seeds have nutritive and<br>calorific value which makes them necessary in diets. They are good<br>sources of edible oils and fats. The amount of energy provide by 1g of<br>fat and oil when fully digested is more than twice as many joules of<br>protein and carbohydrate do. Fats makes meals more satisfying, enrich its<br>flavor and delay the unset of hunger (Odoemelan, 2005). Unfortunately,<br>insufficient availability of animal protein and the costliness of available<br>plant protein sources have also increased the need for research on<br>revealing lesser known under-utilized legumes and oil seeds of nutritive<br>value (Schimid &amp; Ohlrogge, 2002). <br></p>