Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Liver Functions
  • 2.2Allium Ascalonicum - Properties and Uses
  • 2.3Liver Diseases and Their Impact
  • 2.4Previous Research on Allium Ascalonicum
  • 2.5Liver Enzymes: ASP, ALT, AST
  • 2.6Bilirubin: Direct and Total Levels
  • 2.7Mechanisms of Action of Allium Ascalonicum
  • 2.8Effects of Ethanol on Liver Functions
  • 2.9Ethanol Extracts in Traditional Medicine
  • 2.10Summary of Literature Review

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design and Methodology
  • 3.2Selection of Experimental Animals
  • 3.3Preparation of Allium Ascalonicum Ethanolic Extract
  • 3.4Dosage and Administration of Extract
  • 3.5Blood Sample Collection and Analysis
  • 3.6Statistical Analysis Methods
  • 3.7Ethical Considerations
  • 3.8Data Collection Procedures

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Analysis of Liver Function Test Results
  • 4.2Comparison with Control Group
  • 4.3Effects of Allium Ascalonicum Extract on Liver Enzymes
  • 4.4Impact on Bilirubin Levels
  • 4.5Interpretation of Findings
  • 4.6Discussion on Mechanisms of Action
  • 4.7Comparison with Previous Studies
  • 4.8Implications for Liver Health

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusions
  • 5.3Recommendations for Future Research
  • 5.4Practical Applications of Study
  • 5.5Final Thoughts

Project Abstract

<p> </p><div><p>The effect of ethanolic extract of Allium Ascallonicum was evaluated in male and female wistar rat during 14 days after the doses of (300, 500, 700)mg/kg body weight orally. Parameter evaluated include serum ASP, AST, ALT, direct bilirubin and Total bilirubin.20 wistar rats were divided into four groups with weight range of (150±20)g the group 1 is the control group ,group(ii,iii,iv) are treated with the extract in varying concentration of (300,500,700)mg/kg body weight respectively. The result showed that the groups treated with A. ascalonicum insignificantly increased in AST, ALT and ALP parameter by (p&gt;0.05) and insignificant decreased in direct and total bilirubin parameter by (p&gt;0.05).</p><p></p></div><h3></h3><br> <br><p></p>

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