Renal biochemical changes of pregnancy-induced hypertension in pregnant women attending tertiary hospitals in enugu state

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Pregnancy-induced Hypertension
  • 2.2Risk Factors of Pregnancy-induced Hypertension
  • 2.3Pathophysiology of Pregnancy-induced Hypertension
  • 2.4Diagnosis and Management of Pregnancy-induced Hypertension
  • 2.5Renal Biochemical Changes in Pregnancy-induced Hypertension
  • 2.6Impact of Pregnancy-induced Hypertension on Maternal and Fetal Health
  • 2.7Previous Studies on Renal Biochemical Changes in Pregnancy-induced Hypertension
  • 2.8Current Research Gaps in Understanding Renal Biochemical Changes in Pregnancy-induced Hypertension
  • 2.9Role of Nutrition in Managing Pregnancy-induced Hypertension
  • 2.10Future Research Directions in Pregnancy-induced Hypertension

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design and Methodology
  • 3.2Selection of Study Participants
  • 3.3Data Collection Methods
  • 3.4Variables and Measurements
  • 3.5Data Analysis Techniques
  • 3.6Ethical Considerations
  • 3.7Pilot Study Implementation
  • 3.8Data Validation and Reliability Tests

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Overview of Research Findings
  • 4.2Analysis of Renal Biochemical Changes in Pregnancy-induced Hypertension Participants
  • 4.3Correlation of Renal Biomarkers with Disease Severity
  • 4.4Comparison of Renal Function in Normal Pregnant Women and Women with Pregnancy-induced Hypertension
  • 4.5Impact of Treatment on Renal Biomarkers in Pregnancy-induced Hypertension
  • 4.6Discussion on the Implications of Renal Biochemical Changes in Pregnancy-induced Hypertension
  • 4.7Comparison with Previous Studies
  • 4.8Recommendations for Clinical Practice

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Research Findings
  • 5.2Conclusion and Interpretation of Results
  • 5.3Implications for Future Research
  • 5.4Practical Recommendations for Healthcare Professionals
  • 5.5Contribution to the Field of Pregnancy-induced Hypertension Studies

Project Abstract

<p> Pregnancy induced hypertensive disorders have become very common medical complication in Nigeria with its attendant morbidity and mortality. The morbidity and mortality may be associated with its possible effect on the kidneys which was studied. Results of the electrolyte changes from this study showed that there was non-significant difference (p&gt;0.05) in sodium ion concentration of subjects with pregnancy induced hypertension in second and third trimesters (groups 4 and 5 respectively) compared with the control groups (groups 1,2,and 3) who are non-hypertensives in first, second and third trimesters respectively. Similarly, the potassium ion (K+) concentration showed non-significant difference (p&gt;0.05) between the groups 4 and 5 and the control groups even though the highest concentration of potassium ion was seen in the group 4 subjects. From the study, chloride ion (Cl-) and bicarbonate ion (HCO3-) were found to have no significant difference (p&gt;0.05) in concentration between groups 4 and 5 and the control groups. From the estimation of urea and creatinine, it was found that there was no significant difference (p&gt;0.05) in the urea and creatinine concentration between the hypertensives and normotensives in different trimesters however it was found that both urea and creatinine increased in the third trimesters in the hypertensive. The total protein, albumin and globulin level of the subjects in groups 4 and 5 were found to decrease significantly (p&lt;0.05) compared to the control subjects in the corresponding trimesters. <br></p>

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