Eefects of telferia occidentalis and vernonia amygdalina on antioxidants (superoxide dismutase, and catalase) and malondiadehyde in brain, plasma and liver in high sucrose diet fed rats

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Antioxidants
  • 2.2Importance of Superoxide Dismutase
  • 2.3Functions of Catalase
  • 2.4Telferia Occidentalis in Traditional Medicine
  • 2.5Vernonia Amygdalina in Herbal Remedies
  • 2.6Previous Studies on Antioxidants
  • 2.7Effects of High Sucrose Diet on Health
  • 2.8Interactions of Antioxidants with Diet
  • 2.9Mechanisms of Antioxidant Action
  • 2.10Role of Antioxidants in Cellular Health

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Selection of Experimental Subjects
  • 3.3Administration of Telferia Occidentalis and Vernonia Amygdalina
  • 3.4Measurement of Antioxidant Levels
  • 3.5Data Collection Methods
  • 3.6Statistical Analysis Techniques
  • 3.7Ethical Considerations
  • 3.8Research Limitations

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Analysis of Antioxidant Levels in Brain
  • 4.2Analysis of Antioxidant Levels in Plasma
  • 4.3Analysis of Antioxidant Levels in Liver
  • 4.4Comparison of Control and Experimental Groups
  • 4.5Interpretation of Results
  • 4.6Discussion on the Effects of Telferia Occidentalis
  • 4.7Discussion on the Effects of Vernonia Amygdalina
  • 4.8Implications of Findings

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Research Findings
  • 5.2Conclusion and Recommendations
  • 5.3Implications for Future Research

Project Abstract

<p> This study was aimed at investigating the effect of vegetable extract (Juice and pulp) on oxidative stress induced by high sucrose diets on specific antioxidants such as (Catalase, Superoxide Dismutase (SOD) and Malondiadehyde (MDA) in the liver, brain and plasma. 60 albino wistar strain rats were used, The rats were shared into two groups, one part fed with high sucrose diet while others were fed with normal rat chow. Antioxidant status were analysed in the brain, plasma and heart after four weeks of feeding. The result shows the imbalance caused by high sucrose diets having an effect on the antioxidants as the levels of superoxide dismutase, malondialdehyde and catalase in the liver, brain and plasma were significantly reduced (p&lt;0.05). Therefore, moderate consumption of vegetable extracts can modulate antioxidant activity. <br></p>

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