Assessment of the relationship between some trace elements and antioxidant enzymes in under-five children with protein- energy malnutrition

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Trace Elements
  • 2.2Importance of Antioxidant Enzymes
  • 2.3Protein-Energy Malnutrition in Under-Five Children
  • 2.4Relationship between Trace Elements and Antioxidant Enzymes
  • 2.5Previous Studies on Trace Elements and Antioxidant Enzymes
  • 2.6Effects of Trace Element Deficiency on Health
  • 2.7Role of Antioxidant Enzymes in the Body
  • 2.8Impact of Protein-Energy Malnutrition on Children
  • 2.9Factors Influencing Trace Element Levels
  • 2.10Methods of Assessing Antioxidant Enzyme Activity

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Methodology Overview
  • 3.2Research Design and Approach
  • 3.3Sampling Techniques
  • 3.4Data Collection Methods
  • 3.5Data Analysis Procedures
  • 3.6Ethical Considerations
  • 3.7Validity and Reliability of Data
  • 3.8Statistical Tools and Techniques Used

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Summary of Findings
  • 4.2Relationship between Trace Elements and Antioxidant Enzymes
  • 4.3Impact of Protein-Energy Malnutrition on Trace Element Levels
  • 4.4Comparison with Previous Studies
  • 4.5Factors Influencing Antioxidant Enzyme Activity
  • 4.6Discussion on Data Analysis Results
  • 4.7Implications of Findings
  • 4.8Recommendations for Future Research

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Conclusion and Summary
  • 5.2Key Findings Recap
  • 5.3Contributions to Existing Knowledge
  • 5.4Practical Implications
  • 5.5Areas for Future Research

Project Abstract

<p> Assessment of the relationship between some trace elements and antioxidant enzymes was carried out on 98 under-five children with protein-energy malnutrition (PEM) and 98 age- and sex-matched apparently healthy children (control). The malnourished children involve those with Marasmus, Kwashiorkor and Marasmic-kwashiorkor. Venous blood (2ml) was collected from both PEM children and control for biochemical analysis using standard methods. Results obtained show that mean serum total protein (55.76±3.95) and albumin (26.43±2.78) levels and superoxide dismutase (SOD) (1.87±0.32) and glutathione peroxidase (GPx) (42.38±5.03) activities in malnourished children were significantly lower. <br></p>

Project Overview

<p> </p><p><strong>INTRODUCTION</strong></p><p><strong>1.1 Background of the Study</strong></p><p>Severe malnutrition is common among developing countries both in rural and urban areas <strong>(</strong>Psaki <em>et al., </em>2012)<strong>.</strong>It is responsible for at least half of the 7.6 million child‟sdeaths each year indeveloping countries (Park <em>et al.,</em>&nbsp;2012). Children who are poorly nourished suffer up to 160 days of illness each year <strong>(</strong>UNICEF, 2008). Malnutrition magnifies the effects of every disease, including measles and malaria. The estimated proportions of deaths in which malnutrition is an underlying cause are diarrhoea (61%), malaria (57%), pneumonia (52%) and measles (45%) (Black <em>et al.,</em>&nbsp;2003). Protein-energy malnutrition (PEM) is one of the most prevalent and devastating forms of malnutrition in the world (Whitney and Rolfes, 2008).</p> <br><p></p>

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