ASSESSMENT OF THE RELATIONSHIP BETWEEN SOME TRACE ELEMENTS AND ANTIOXIDANT ENZYMES IN UNDER-FIVE CHILDREN WITH PROTEIN- ENERGY MALNUTRITION

 

Table Of Contents


Chapter ONE

INTRODUCTION

  • 1.1Introduction
  • 1.2Background of Study
  • 1.3Problem Statement
  • 1.4Objective of Study
  • 1.5Limitation of Study
  • 1.6Scope of Study
  • 1.7Significance of Study
  • 1.8Structure of the Research
  • 1.9Definition of Terms

Chapter TWO

LITERATURE REVIEW

  • 2.1Overview of Trace Elements
  • 2.2Importance of Antioxidant Enzymes
  • 2.3Protein-Energy Malnutrition in Children
  • 2.4Relationship Between Trace Elements and Antioxidant Enzymes
  • 2.5Studies on Trace Elements and Antioxidant Enzymes in Children
  • 2.6Effects of Malnutrition on Antioxidant Enzymes
  • 2.7Impact of Trace Element Deficiencies on Children
  • 2.8Role of Antioxidants in Children's Health
  • 2.9Strategies for Improving Nutritional Status in Children
  • 2.10Current Research Gaps in Trace Elements and Antioxidant Enzymes

Chapter THREE

RESEARCH METHODOLOGY

  • 3.1Research Design
  • 3.2Population and Sample Selection
  • 3.3Data Collection Methods
  • 3.4Measurement of Trace Elements and Antioxidant Enzymes
  • 3.5Data Analysis Techniques
  • 3.6Ethical Considerations
  • 3.7Research Limitations
  • 3.8Validation of Research Instruments

Chapter FOUR

DATA PRESENTATION AND ANALYSIS

  • 4.1Overview of Research Findings
  • 4.2Analysis of Trace Element Levels
  • 4.3Evaluation of Antioxidant Enzyme Activity
  • 4.4Correlation Between Trace Elements and Antioxidant Enzymes
  • 4.5Comparison with Previous Studies
  • 4.6Discussion on Nutritional Implications
  • 4.7Implications for Public Health Policies
  • 4.8Recommendations for Future Research

Chapter FIVE

SUMMARY, CONCLUSION AND RECOMMENDATIONS

  • 5.1Summary of Findings
  • 5.2Conclusions
  • 5.3Implications for Practice
  • 5.4Recommendations for Policy
  • 5.5Contributions to the Field
  • 5.6Reflection on the Research Process
  • 5.7Areas for Future Research
  • 5.8Closing Remarks

Project Abstract

<p> </p><p>Assessment of the relationship between some trace elements and antioxidant enzymes was carried out on 98 under-five children with protein-energy malnutrition (PEM) and 98 age- and sex-matched apparently healthy children (control). The malnourished children involve those with Marasmus, Kwashiorkor and Marasmic-kwashiorkor. Venous blood (2ml) was collected from both PEM children and control for biochemical analysis using standard methods. Results obtained show that mean serum total protein (55.76±3.95) and albumin (26.43±2.78) levels and superoxide dismutase (SOD) (1.87±0.32) and glutathione peroxidase (GPx) (42.38±5.03) activities in malnourished children were significantly lower.</p><br> <br><p></p>

Project Overview

<p> </p><p>Severe malnutrition is common among developing countries both in rural and urban areas (Psaki et al., 2012).It is responsible for at least half of the 7.6 million child‟sdeaths each year indeveloping countries (Park et al., 2012). Children who are poorly nourished suffer up to 160 days of illness each year (UNICEF, 2008). Malnutrition magnifies the effects of every disease, including measles and malaria. The estimated proportions of deaths in which malnutrition is an underlying cause are diarrhoea (61%), malaria (57%), pneumonia (52%) and measles (45%) (Black et al., 2003). Protein-energy malnutrition (PEM) is one of the most prevalent and devastating forms of malnutrition in the world (Whitney and Rolfes, 2008).</p><p></p><br> <br><p></p>

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