<p>1. Introduction<br> 1.1 Background<br> 1.2 Objectives<br>2. Biochemical Changes during Aging<br> 2.1 DNA Damage and Repair<br> 2.2 Protein Modifications and Aggregation<br> 2.3 Lipid Metabolism and Aging<br> 2.4 Cellular Metabolism and Aging<br>3. Oxidative Stress and Aging<br> 3.1 Reactive Oxygen Species (ROS)<br> 3.2 Antioxidant Defense Systems<br> 3.3 Oxidative Damage and Aging<br>4. Inflammation and Aging<br> 4.1 Chronic Low-Grade Inflammation<br> 4.2 Inflammatory Signaling Pathways<br> 4.3 Inflammaging: Inflammation and Aging<br>5. Cellular Senescence and Aging<br> 5.1 Senescence-associated Secretory Phenotype (SASP)<br> 5.2 Telomere Shortening and Senescence<br> 5.3 Senescence and Age-Related Diseases<br></p>
This project aims to explore the biochemistry of aging, a complex and multifaceted process that affects all living organisms. The project will investigate the biochemical changes that occur during aging, including alterations in DNA, proteins, lipids, and cellular metabolism. The project will also examine the role of oxidative stress, inflammation, and cellular senescence in the aging process. By gaining a deeper understanding of the biochemistry of aging, this project will contribute to the development of strategies to promote healthy aging and prevent age-related diseases.
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