Home / Biochemistry / Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats

Study on the effect of allium ascalonicum ethanolic extract on liver functions: asp, alt, ast, direct and total bilirubin in adult wistar rats

 

Table Of Contents


Chapter ONE

1.1 Introduction
1.2 Background of the Study
1.3 Problem Statement
1.4 Objectives of the Study
1.5 Limitations of the Study
1.6 Scope of the Study
1.7 Significance of the Study
1.8 Structure of the Research
1.9 Definition of Terms

Chapter TWO

2.1 Overview of Liver Functions
2.2 Allium Ascalonicum: Botanical Description
2.3 Traditional Uses of Allium Ascalonicum
2.4 Phytochemical Composition of Allium Ascalonicum
2.5 Pharmacological Properties of Allium Ascalonicum
2.6 Previous Studies on Allium Ascalonicum
2.7 Liver Function Tests (ASP, ALT, AST, Bilirubin)
2.8 Importance of Monitoring Liver Functions
2.9 Experimental Models for Liver Function Studies
2.10 Summary of the Literature Review

Chapter THREE

3.1 Research Design
3.2 Sampling Technique
3.3 Data Collection Methods
3.4 Ethical Considerations
3.5 Data Analysis Techniques
3.6 Variables and Measurements
3.7 Statistical Tools
3.8 Instrumentation

Chapter FOUR

4.1 Data Presentation and Analysis
4.2 Effects of Allium Ascalonicum Extract on Liver Functions
4.3 Comparison with Control Group
4.4 Interpretation of Results
4.5 Discussion on Findings
4.6 Implications of the Study
4.7 Recommendations for Future Research
4.8 Limitations of the Study

Chapter FIVE

5.1 Summary of Findings
5.2 Conclusions
5.3 Contributions to Knowledge
5.4 Practical Implications
5.5 Recommendations for Practice
5.6 Recommendations for Policy
5.7 Areas for Future Research
5.8 Closing Remarks

Thesis Abstract

The effect of ethanolic extract of Allium Ascallonicum was evaluated in male and female wistar rat during 14 days after the doses of (300, 500, 700)mg/kg body weight orally. Parameter evaluated include serum ASP, AST, ALT, direct bilirubin and Total bilirubin.20 wistar rats were divided into four groups with weight range of (150±20)g the group 1 is the control group ,group(ii,iii,iv) are treated with the extract in varying concentration of (300,500,700)mg/kg body weight respectively. The result showed that the groups treated with A. ascalonicum insignificantly increased in AST, ALT and ALP parameter by (p>0.05) and insignificant decreased in direct and total bilirubin parameter by (p>0.05).



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