Home / Biochemistry / Hepatotoxicity of the ethanolic extracts of enantia chlorantha root on wistar albino rats

Hepatotoxicity of the ethanolic extracts of enantia chlorantha root on wistar albino rats

 

Table Of Contents


<p> </p><div><p>TITLE PAGE ICERTIFICATION IIDEDICATION IIIACKNOWLEDGEMENT IVTABLE OF CONTENT VABSTRACT IX</p><p>CHAPTER ONE1.0 INTRODUCTION 11.1 BACKGROUND OF THE STUDY 11.2 AIMS AND OBJECTIVES 61.3 STATEMENT OF PROBLEM 71.4 LIMITATION OF STUDY 71.5 SIGNIFICANCE OF THE STUDY 8</p><p>CHAPTER TWO2.0 LITERATURE REVIEW 92.1 GENERAL DESCRIPTION OF Enantia chlorontha 102.2 ECOLOGICAL DISTRIBUTION OFEnantia chlorantha 102.3 MANAGEMENT AND PROPAGATION PRACTICES 112.4 FUNCTIONAL USES 122.5 TOXICITY 132.6 HEPATOTOXICITY 172.7 LIVER 202.7.1 LIVER ENZYME 222.7.2 SOME PATTERN OF LIVER INJURY 232.7.3 TREATMENT/PROGNOSIS OF LIVER DAMAGE 282.8 THE ALBINO RATS 292.9 PHYTOCHEMICAL COMPOUNDS 31</p><p>CHAPTER THREE3.0 MATERIALS AND METHODS 323.1 COLLECTION, IDENTIFICATION ANDPROCESSING OF PLANT MATERIAL 323.1.1 EXTRACTION OF PLANT MATERIAL 333.1.2 DETERMINATION OF THE WEIGHT OFDRIED EXTRACT 343.2 PHYTOCHEMCIAL ANALYSIS 353.3 EXPERIMENTAL ANIMAL 433.4 DETERMINATION OF DOSAGE OF THE PLANTEXTRACT FOR ANIMAL FEEDING 433.5 GROUPING OF ANIMAL AND ADMINISTRATIONOF PLANT EXTRACT 443.6 FEEDING METHOD 453.7 PROCEDURES FOR BLOOD SAMPLE COLLECTION 463.7.1 ALANINE AMINOTRANSFERASE TEST (ALT)METHOD FOR ALT TEST 473.7.2 ASPARTATE ANIMOTRANSFERASE: (AST)METHOD FOR AST TEST 483.7.3 ALKALINE PHOUSPHATASE: (ALP)METHOD FOR ALP TEST 49CHAPTER FOUR4.0 RESULTS 504.1 RESULT OF THE PHOTOCHEMICALANALYSIS OF THE ETHANOLIC EXTRACTOF Enantia chlorontha 504.2 HEPATOTOXICITY ASSAY 55</p><p>CHAPTER FIVE5.1 DISCUSSION 585.2 CONCLUSION 605.3 RECOMMENDATION 60</p><p>REFERENCES 61.</p><p></p></div><h3></h3><br> <br><p></p>

Thesis Abstract

The root of Enantia chlorontha was assayed for its hepatotoxicity effect. Extacts from the root were made using 95% ethanol. The root extracts were administered orally to 15 wistar albino rats and varying doses. 5 rats were kept as control group. The effect of the extracts was determined by assaying for the levels of serum-liver enzymes acting as biochemical makers. Liver enzymes assayed included Aspartate aminotransferase (AST), Alanin aminiotransferase (ALT) and alkaline phophatase (ALP). Comparison of the enzyme levels of the control group with these of the group administered with the rot extract revealed a significant elevation of liver enzyme levels (P

Thesis Overview

Blazingprojects Mobile App

📚 Over 50,000 Research Thesis
📱 100% Offline: No internet needed
📝 Over 98 Departments
🔍 Thesis-to-Journal Publication
🎓 Undergraduate/Postgraduate Thesis
📥 Instant Whatsapp/Email Delivery

Blazingprojects App

Related Research

Biochemistry. 4 min read

Analysis of the role of microRNAs in cancer progression...

The project titled "Analysis of the role of microRNAs in cancer progression" aims to investigate the intricate role of microRNAs in the progression of...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Investigating the role of microRNAs in regulating gene expression in cancer cells....

**Research Overview: Investigating the Role of microRNAs in Regulating Gene Expression in Cancer Cells** Cancer is a complex disease characterized by uncontrol...

BP
Blazingprojects
Read more →
Biochemistry. 3 min read

Exploring the role of microRNAs in regulating gene expression in cancer cells...

The project titled "Exploring the role of microRNAs in regulating gene expression in cancer cells" aims to investigate the intricate mechanisms by whi...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Exploring the Role of MicroRNAs in Cancer Progression: Mechanisms and Therapeutic Po...

The project titled "Exploring the Role of MicroRNAs in Cancer Progression: Mechanisms and Therapeutic Potential" aims to investigate the intricate inv...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Exploring the role of microRNAs in cancer progression and potential therapeutic appl...

The project titled "Exploring the role of microRNAs in cancer progression and potential therapeutic applications" aims to investigate the intricate in...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Exploring the role of gut microbiota in metabolic diseases...

The project titled "Exploring the role of gut microbiota in metabolic diseases" aims to investigate the intricate relationship between gut microbiota ...

BP
Blazingprojects
Read more →
Biochemistry. 4 min read

Analysis of enzyme kinetics in cancer cells....

The project titled "Analysis of enzyme kinetics in cancer cells" aims to investigate the unique enzymatic activities present in cancer cells and how t...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Analysis of enzyme kinetics in cancer cells....

The project titled "Analysis of enzyme kinetics in cancer cells" aims to investigate the enzymatic processes within cancer cells to better understand ...

BP
Blazingprojects
Read more →
Biochemistry. 2 min read

Investigating the Effects of Different pH Levels on Enzyme Activity in Human Saliva...

The project titled "Investigating the Effects of Different pH Levels on Enzyme Activity in Human Saliva" aims to explore the relationship between pH l...

BP
Blazingprojects
Read more →
WhatsApp Click here to chat with us