Investigating the role of biochemistry in drug metabolism in prostate cancer
Table Of Contents
<p>1. Introduction<br> 1.1 Background and significance<br> 1.2 Objectives of the study<br>2. Drug metabolism in prostate cancer<br> 2.1 Role of drug-metabolizing enzymes<br> 2.2 Altered drug metabolism in prostate cancer<br>3. Drug-metabolizing enzymes in prostate cancer<br> 3.1 Cytochrome P450 enzymes<br> 3.2 UDP-glucuronosyltransferases<br> 3.3 Glutathione S-transferases<br>4. Impact of altered drug metabolism on drug efficacy and toxicity<br> 4.1 Drug response in prostate cancer<br> 4.2 Drug toxicity in prostate cancer<br>5. Experimental methods<br> 5.1 Cell culture and treatment<br> 5.2 Expression analysis of drug-metabolizing enzymes<br> 5.3 Enzyme activity assays <br></p>
Thesis Abstract
<p> Prostate cancer is a significant health concern, and drug metabolism plays a critical role in determining the response to anticancer drugs. This project aims to investigate the role of biochemistry in drug metabolism in prostate cancer. By studying the expression and activity of drug-metabolizing enzymes in prostate cancer cells, as well as the impact of altered drug metabolism on drug efficacy and toxicity, this research will provide insights into the molecular mechanisms underlying drug metabolism in prostate cancer. <br></p>Thesis Overview
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