Project Abstract

Computed Tomography (CT) imaging has revolutionized the field of medical diagnostics, providing healthcare professionals with detailed, three-dimensional images of the body's internal structures. However, the use of ionizing radiation in CT scans has raised concerns about the potential risks associated with radiation exposure, particularly for patients who undergo multiple scans over their lifetime. This project aims to explore and optimize radiation dose reduction techniques in CT imaging, with the goal of minimizing the health risks while maintaining the diagnostic quality of the images. The importance of this project cannot be overstated. Exposure to ionizing radiation, even at low levels, can have long-term consequences, such as an increased risk of cancer development. This is especially concerning for vulnerable populations, such as children and pregnant women, who may require repeated CT scans for medical conditions. By developing and implementing effective radiation dose reduction strategies, this project has the potential to significantly improve patient safety and reduce the overall healthcare burden associated with radiation-induced health issues. The project will focus on three key areas image acquisition, image reconstruction, and dose optimization. In the image acquisition stage, the researchers will investigate the effects of various scanning parameters, such as tube voltage, current, and exposure time, on the radiation dose and image quality. They will explore techniques like automated tube current modulation, which adjusts the X-ray output based on the patient's anatomy, and iterative reconstruction algorithms, which can enhance image quality while reducing radiation exposure. In the image reconstruction phase, the team will explore advanced reconstruction methods, such as model-based iterative reconstruction (MBIR) and deep learning-based approaches, to improve the accuracy and resolution of the CT images while minimizing the radiation dose. These techniques have the potential to enable high-quality imaging with significantly lower radiation exposure compared to traditional filtered back-projection methods. Finally, the project will address the optimization of the overall radiation dose in CT imaging. This will involve developing decision-support tools and guidelines to help healthcare providers select the appropriate imaging modality and protocol based on the specific clinical needs of the patient. This will ensure that the benefits of the CT scan outweigh the potential risks and that the radiation dose is kept as low as reasonably achievable (ALARA) without compromising diagnostic accuracy. Throughout the project, the researchers will collaborate with clinicians, medical physicists, and radiation safety experts to ensure that the proposed solutions are clinically relevant, technically feasible, and in compliance with regulatory standards. The project's findings will be disseminated through peer-reviewed publications, conference presentations, and educational materials to share the knowledge and best practices with the broader medical imaging community. By optimizing radiation dose reduction techniques in CT imaging, this project has the potential to significantly improve patient safety, reduce the overall healthcare costs associated with radiation-induced complications, and contribute to the advancement of the field of medical imaging. The successful implementation of these strategies will not only benefit individual patients but also have a positive impact on public health and the sustainability of the healthcare system.

Project Overview