Project Abstract

Abstract
The increasing prevalence of antibiotic resistance among pathogenic bacteria has become a significant global health concern, necessitating the exploration of alternative antimicrobial agents. Plant extracts have been recognized for their potential antibacterial properties due to the presence of bioactive compounds. This research project aims to investigate the antibacterial properties of various plant extracts against pathogenic bacteria and evaluate their potential as alternative antimicrobial agents. The study will commence with a comprehensive review of the existing literature on plant extracts with antibacterial properties and their mechanisms of action. Various plant species known for their antimicrobial activities will be identified and selected for the experimental phase of the study. The plant extracts will be obtained through extraction methods such as maceration, Soxhlet extraction, or steam distillation, followed by phytochemical analysis to identify the bioactive compounds present. The antibacterial efficacy of the plant extracts will be assessed through agar well diffusion and minimum inhibitory concentration (MIC) assays against a panel of pathogenic bacteria, including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and others. The results obtained will be compared with standard antibiotics to determine the relative potency of the plant extracts. Furthermore, the study will investigate the potential synergistic effects of combining plant extracts with conventional antibiotics to enhance antibacterial activity and potentially combat antibiotic resistance. The mechanisms of action of the plant extracts will be elucidated through additional experiments, such as membrane permeability assays and biofilm inhibition studies. The findings of this research project will contribute to the growing body of knowledge on natural antimicrobial agents and their applications in combating bacterial infections. The identification of potent plant extracts with antibacterial properties can pave the way for the development of novel therapeutic agents or adjuvants for existing antibiotics. Additionally, the study will provide insights into the mechanisms of action of plant compounds against pathogenic bacteria, shedding light on their potential as future antimicrobial agents. In conclusion, this research project aims to explore the antibacterial properties of plant extracts on pathogenic bacteria and elucidate their potential as alternative antimicrobial agents. The results obtained will not only contribute to the scientific understanding of natural antimicrobial agents but also have practical implications for the development of novel therapeutic strategies to combat antibiotic resistance.

Project Overview