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Antibiotics resistance profile of escherichia coli isolated from apparently healthy domestic livestock

 

Table Of Contents


Chapter ONE

1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms

Chapter TWO

2.1 Overview of Antibiotics Resistance
2.2 Escherichia coli in Domestic Livestock
2.3 Antibiotics Usage in Livestock Farming
2.4 Resistance Mechanisms in Escherichia coli
2.5 Global Impact of Antibiotics Resistance
2.6 Studies on Antibiotics Resistance in Livestock
2.7 Factors Contributing to Antibiotics Resistance
2.8 Strategies to Combat Antibiotics Resistance
2.9 Role of Veterinary Medicine in Antibiotics Use
2.10 Future Perspectives on Antibiotics Resistance

Chapter THREE

3.1 Research Design
3.2 Sampling Techniques
3.3 Data Collection Methods
3.4 Data Analysis Procedures
3.5 Ethical Considerations
3.6 Validity and Reliability
3.7 Research Limitations
3.8 Research Assumptions

Chapter FOUR

4.1 Overview of Research Findings
4.2 Antibiotics Resistance Profile in Domestic Livestock
4.3 Distribution of Escherichia coli Strains
4.4 Factors Influencing Resistance Patterns
4.5 Comparison with Previous Studies
4.6 Discussion on Resistance Mechanisms
4.7 Implications for Livestock Health
4.8 Recommendations for Future Research

Chapter FIVE

5.1 Conclusion and Summary
5.2 Summary of Findings
5.3 Contributions to the Field
5.4 Practical Implications
5.5 Recommendations for Practice
5.6 Areas for Future Research

Project Abstract

This study was conducted to determine the antibiotic resistance profile of Escherichial Coli isolate from apparently healthy domestic livestock viz cow, goats and chicken from Osun State Nigeria. E. Coli was isolated using Eosin methylene Blue Agar (EMB) and identified by conventional microbiological technique. The isolate were tested against 14 antibiotics using the disc diffusion method. A total of 42 different antibiotics resistance profile were observed with each isolate showing resistance to at least four or more drugs tested. Generally, the E. coli isolates showed resistance rates of 93.8% to Ampicilin; 15.3% to Chloramphenicol, 52.7% to cloxacillin, 74.3% Erythromycin, 20.9% to Gentamicin, 53.8% to Penicillin, 17.7% to Streptomycin, 67.3% to Tetracyclin, 21.1% to Ceftazidine 70.7% to Cefuroxine, 20.5% to Cefixine, 28.8% to Ofloxacine, 58.6% to Augmentin, 27.2% to Nitorfurantion 27.3% to Ciprofloxacin. Statistical analysis showed that average number of resistance phenotypes per isolate was significantly higher for cow compared with poultry. A significant public health concern observed in this study is that multi drug resistant commensal E. Coli strains may constitute a potential reservoir of resistance genes that could be transferred to pathogenic bacteria.    

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