<p> </p><p>Title page – – – – – -i</p><p>Approval page – – – – – -ii</p><p>Dedication – – – – – -iii</p><p>Acknowledgment – – – – – -iv</p><p>Abstract – – – – – -v</p><p>Table of Content – – – – – -vi</p><p><b>

Chapter ONE

</b></p><p>1.0 Introduction – – – – – -1</p><p>1.1 Crateva adansonii – – – – – -2</p><p>1.2 Research Aim &amp; Objectives – – – – – -2</p><p><b>

Chapter TWO

</b></p><p>2.1 Definition of Inflammation – – – – – -3</p><p>2.1.1 What is Anti-inflammation? – – – – – -3</p><p>Types of Inflammation (Acute and Chronic) – – – -4</p><p>2.1.2 Steroid and non-steroidal anti-inflammatory drugs – – -5</p><p>2.1.3 Immune selective anti-inflammatory derivative – – -6</p><p>2.1.4 Pain – – – – – -7</p><p>2.1.5 Long effect of inflammation – – – – – -8</p><p>2.1.6 Ice Treatment of Inflammation – – – – – – 9</p><p>2.1.7 Nutritional sources of anti-inflammatory compounds – -9</p><p>2.2 Vascular event in inflammation- – – – – -9</p><p>2.2.1 Vasoconstriction – – – – – -10</p><p>2.2.2 Vasodilation – – – – – -11</p><p>2.2.3 Vascular permeability – – – – – -11</p><p>2.3 Cellular event – – – – – -14</p><p>2.3.1 Leukocytes migration as specific Hemoral/cellular immunity- – – – – -14</p><p>2.4 Mediators of inflammation – – – – – -17</p><p>2.4.1 Cell derived mediators of inflammation- – – – -18</p><p>2.4.2 Histamine – – – – – -19</p><p>2.4.3 Cytokines – – – – – -19</p><p>2.4.4 Serotonin (5-hydroxytryptamine)- – – – – -19</p><p>2.4.5 Platelet-Activating factor (PAF)- – – – – -20</p><p>2.4.6 Arachidonic Acid (AA – – – – – -20</p><p>2.4.7 Free radicals as mediators of inflammation- – – – -22</p><p>2.4.8 Nitric Acid (NO) – – – – – -23</p><p>2.4.9 Reactive Oxygen Species (ROS)- – – – – –</p><p><b>

Chapter THREE

</b></p><p>3.1 Materials, equipments and apparatus – – – – -25</p><p>3.2 Chemical, reagents and practical technique- – – -25</p><p>3.2.1 Methanol – – – – – -25</p><p>3.2.2 N-Hexane – – – – – -26</p><p>3.2.3 Ethyl acetate – – – – – -27</p><p>3.2.4 Dichloromethane – – – – – -28</p><p>3.3 Methodology – – – – – -29</p><p>3.3.1 Collection and preparation of plant- – – – – -29</p><p>3.3.2 Extraction and fractionation of plant materials- – – -29</p><p>3.4 Phytochemical Analysis – – – – – -30</p><p>3.5 Column chromatography – – – – – -32</p><p>3.6 Thin layer chromatography – – – – – -33</p><p>3.7 How to run TCL plate – – – – – -34</p><p><b>

Chapter FOUR

</b></p><p>4.0 Experimental result – – – – – -38</p><p>4.1 Tabular and graphical representation of effect of anti-inflammatory effect of</p><p>Crateva adansonii dichloromethane extract- – – – -38</p><p>4.2 Phytochemical analysis of extract (result) – – – – -40</p><p><b>

Chapter FIVE

</b></p><p>5.0 Discussion – – – – – -41</p><p>5.1 Conclusion – – – – – -41</p><p><b>REFERENCE – – – – – -42</b></p><p><b>APPENDIX I</b></p><p><b>APPENDIX II</b></p><p><b>APPENDIX III</b></p><p><b>APPENDIX IV</b></p><p><b>APPENDIX V</b></p> <br><p></p>