<p> </p><p><strong><em>Abstract &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</em></strong></p><p><strong>

Chapter ONE

</strong></p><p>1.0 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Introduction and Literature Review</p><p>1.1 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Fibroid</p><p>1.1.1 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Location and classification of fibroid</p><p>1.1.2 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Pathogenesis and Pathophysiology</p><p>1.1.2.1 &nbsp; &nbsp; &nbsp; Pathogenesis</p><p>1.1.2.2 &nbsp; &nbsp; &nbsp; Pathophysiology</p><p>1.1.3 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Signs, Symptoms and Causes of fibroid</p><p>1.2 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Arginase</p><p>1.2.1 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Role of arginase in human body</p><p>1.2.2 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Aginase activities in Benign tumour</p><p>1.2.3 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Arginase II expression in benign and malignant prostate tissue</p><p>1.3 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Glutathione (GSH)</p><p>1.3.1 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Role of glutathione as an antioxidant</p><p>1.3.2 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Glutathione response to exercise</p><p>1.4 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Sodium citrate</p><p>1.5 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Aims and objectives</p><p>

Chapter TWO

</p><p>2.0 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Materials and Methods</p><p>2.1 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Materials</p><p>2.1.1 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Apparatus</p><p>2.2 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Methods</p><p>2.2.1 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Preparation of buffers and reagents</p><p>2.3 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Biochemical test</p><p>2.3.1 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Arginase assay</p><p>2.3.2 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Protein standard curve</p><p>2.3.3 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Effect of Glutathione (GSH)</p><p>

Chapter THREE

</p><p>3.0 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Results</p><p>

Chapter FOUR

</p><p>4.0 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Discussion, Conclusion and Recommendation</p><p>4.1 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Discussion</p><p>4.2 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Conclusion</p><p>4.3 &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Recommendations</p><p>References</p><p>LIST OF FIGURES</p><p>Figure 1 – &nbsp; &nbsp; Uterine Fibroid</p><p>Figure 2 – &nbsp; Hydrolysis of L-arginine</p><p>Figure 3 – &nbsp; Structure of arginase and the active site</p><p>Figure 4 – &nbsp; Showing the effect of sodium citrate on arginase from human fibroid tissue</p><p>Figure 5 – &nbsp; Showing the effect of Glutathione (GSH) on arginase from human fibroid tissue.</p> <br><p></p>