Thesis Abstract

Abstract
The human gut microbiota plays a crucial role in maintaining overall health by influencing various physiological processes, including immune response. Probiotics, live microorganisms that confer health benefits to the host when administered in adequate amounts, have gained significant attention for their potential in modulating gut microbiota composition and immune response. This thesis aims to explore the role of probiotics in modulating gut microbiota composition and immune response, with a focus on understanding the mechanisms underlying these effects. Chapter one provides an introduction to the study, outlining the background, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of terms. Chapter two presents a comprehensive literature review that examines existing research on probiotics, gut microbiota, and immune response, highlighting key findings and gaps in knowledge. Chapter three details the research methodology, including study design, participant selection, probiotic intervention methods, data collection, and analysis procedures. Chapter four presents a detailed discussion of the findings, analyzing the impact of probiotics on gut microbiota composition and immune response based on the study results. This chapter explores the mechanisms through which probiotics exert their effects on the gut microbiota and immune system, shedding light on the potential therapeutic applications of probiotics in promoting gut health and immune function. Finally, chapter five offers a conclusion and summary of the thesis, summarizing the key findings, discussing the implications of the research, and suggesting areas for future investigation. Overall, this thesis contributes to the growing body of knowledge on the role of probiotics in modulating gut microbiota composition and immune response, providing valuable insights that may inform the development of novel probiotic-based interventions for improving human health.

Thesis Overview

The research project titled "Exploring the role of probiotics in modulating gut microbiota composition and immune response" aims to investigate the intricate relationship between probiotics, gut microbiota composition, and immune response in the human body. Probiotics are live microorganisms that, when consumed in adequate amounts, confer health benefits to the host. The gut microbiota, a diverse community of microorganisms residing in the gastrointestinal tract, plays a crucial role in maintaining gut health and influencing overall well-being. Furthermore, the immune response is a complex system that protects the body from harmful pathogens and maintains homeostasis. This research project seeks to delve into how probiotics interact with the gut microbiota to potentially modulate its composition and subsequently influence the immune response. By exploring this relationship, the study aims to provide valuable insights into the mechanisms by which probiotics exert their beneficial effects on human health. Understanding these mechanisms can have significant implications for the development of novel therapeutic strategies for various health conditions, including gastrointestinal disorders, immune-related diseases, and metabolic disorders. The project will employ a multidisciplinary approach, integrating knowledge from microbiology, immunology, and nutrition to comprehensively investigate the role of probiotics in modulating gut microbiota composition and immune response. Experimental methods such as in vitro and in vivo studies, next-generation sequencing techniques, and immunological assays will be utilized to analyze the effects of probiotics on gut microbiota composition and immune function. Overall, this research project aims to contribute to the growing body of knowledge on the potential benefits of probiotics in promoting gut health and modulating immune responses. The findings from this study have the potential to inform future research directions, clinical interventions, and public health strategies aimed at enhancing human health through the manipulation of the gut microbiota using probiotics.