Thesis Abstract

The rise of antibiotic-resistant bacteria poses a significant global health threat, necessitating the exploration of alternative antimicrobial agents. This thesis investigates the potential antimicrobial activity of plant extracts against antibiotic-resistant bacteria. The study aims to contribute to the development of novel strategies to combat antibiotic resistance by exploring the antimicrobial properties of plant extracts. The research methodology involved the collection and preparation of plant extracts, screening for antimicrobial activity using various assays, and identifying the most effective extracts against a panel of antibiotic-resistant bacteria. The results revealed promising antimicrobial activity in several plant extracts, highlighting their potential as alternative antimicrobial agents. The literature review provides a comprehensive overview of antibiotic resistance, the mechanisms of action of plant antimicrobial compounds, and previous studies on the antimicrobial activity of plant extracts. The findings of this study contribute to the growing body of research on natural antimicrobial agents and their potential applications in combating antibiotic resistance. The discussion of findings delves into the implications of the study results, the potential mechanisms of action of plant antimicrobial compounds, and the future directions for research in this field. The significance of this research lies in its potential to advance our understanding of plant-based antimicrobial agents and their role in addressing the challenge of antibiotic resistance. In conclusion, this thesis demonstrates the potential antimicrobial activity of plant extracts against antibiotic-resistant bacteria, highlighting the importance of further research in this area. The findings of this study contribute to the growing body of knowledge on natural antimicrobial agents and their potential applications in combating antibiotic resistance.

Thesis Overview

The research project titled "Investigating the potential antimicrobial activity of plant extracts against antibiotic-resistant bacteria" aims to address the pressing issue of antibiotic resistance by exploring the use of plant-derived compounds as alternative antimicrobial agents. Antibiotic resistance poses a significant threat to public health globally, leading to increased morbidity, mortality, and healthcare costs. The overuse and misuse of antibiotics have accelerated the development of resistance among bacterial pathogens, rendering many conventional antibiotics ineffective. In this study, the focus is on plant extracts, which have long been recognized for their diverse bioactive compounds with potential antimicrobial properties. Plants produce a wide array of secondary metabolites, such as alkaloids, flavonoids, terpenoids, and phenolics, which exhibit antimicrobial activity against a range of bacterial strains. By investigating the antimicrobial potential of these plant extracts, the research aims to identify novel compounds that can effectively combat antibiotic-resistant bacteria. The project will involve a comprehensive literature review to gather existing knowledge on the antimicrobial properties of plant extracts and their mechanisms of action against bacterial pathogens. Subsequently, experimental studies will be conducted to evaluate the antimicrobial activity of selected plant extracts against a panel of antibiotic-resistant bacteria. The research methodology will include extraction techniques, antimicrobial assays, and characterization of bioactive compounds present in the plant extracts. The findings of this study are expected to contribute valuable insights into the potential use of plant extracts as alternative antimicrobial agents in the fight against antibiotic resistance. By identifying and characterizing bioactive compounds with potent antimicrobial properties, this research could pave the way for the development of novel antimicrobial therapies derived from natural sources. Ultimately, the goal is to provide new strategies for combating antibiotic-resistant bacteria and reducing the reliance on conventional antibiotics. Through this research project, we aim to shed light on the untapped potential of plant extracts as a source of novel antimicrobial agents and contribute to the ongoing efforts to address the global challenge of antibiotic resistance. The findings of this study have the potential to impact public health, pharmaceutical development, and the future of antimicrobial therapy.