Home / Microbiology / Antibiotics resistance profile of escherichia coli isolated from apparently healthy domestic livestock

Antibiotics resistance profile of escherichia coli isolated from apparently healthy domestic livestock

 

Table Of Contents


Chapter ONE

1.1 Introduction
1.2 Background of study
1.3 Problem Statement
1.4 Objective of study
1.5 Limitation of study
1.6 Scope of study
1.7 Significance of study
1.8 Structure of the research
1.9 Definition of terms

Chapter TWO

2.1 Overview of Antibiotics
2.2 Antibiotics Resistance Mechanisms
2.3 Factors Contributing to Antibiotics Resistance
2.4 Impact of Antibiotics Resistance on Public Health
2.5 Antibiotics Usage in Livestock
2.6 Antibiotics Resistance in Escherichia coli
2.7 Previous Studies on Antibiotics Resistance in Livestock
2.8 Strategies to Combat Antibiotics Resistance
2.9 Regulations on Antibiotics Use in Livestock
2.10 Future Directions in Antibiotics Resistance Research

Chapter THREE

3.1 Research Design
3.2 Sampling Techniques
3.3 Data Collection Methods
3.4 Data Analysis Procedures
3.5 Ethical Considerations
3.6 Research Validity and Reliability
3.7 Limitations of the Methodology
3.8 Research Instrumentation

Chapter FOUR

4.1 Data Presentation and Analysis
4.2 Antibiotics Resistance Profile of Escherichia coli in Livestock
4.3 Comparison of Antibiotics Resistance Patterns
4.4 Factors Influencing Antibiotics Resistance
4.5 Discussion on Antibiotics Resistance Trends
4.6 Implications for Livestock Health
4.7 Recommendations for Future Interventions
4.8 Areas for Further Research

Chapter FIVE

5.1 Summary of Findings
5.2 Conclusions drawn from the Research
5.3 Implications for Livestock Industry
5.4 Contribution to Scientific Knowledge
5.5 Recommendations for Policy and Practice

Thesis Abstract

This study was conducted to determine the antibiotic resistance profile of Escherichial Coli isolate from apparently healthy domestic livestock viz cow, goats and chicken from Osun State Nigeria. E. Coli was isolated using Eosin methylene Blue Agar (EMB) and identified by conventional microbiological technique. The isolate were tested against 14 antibiotics using the disc diffusion method. A total of 42 different antibiotics resistance profile were observed with each isolate showing resistance to at least four or more drugs tested. Generally, the E. coli isolates showed resistance rates of 93.8% to Ampicilin; 15.3% to Chloramphenicol, 52.7% to cloxacillin, 74.3% Erythromycin, 20.9% to Gentamicin, 53.8% to Penicillin, 17.7% to Streptomycin, 67.3% to Tetracyclin, 21.1% to Ceftazidine 70.7% to Cefuroxine, 20.5% to Cefixine, 28.8% to Ofloxacine, 58.6% to Augmentin, 27.2% to Nitorfurantion 27.3% to Ciprofloxacin. Statistical analysis showed that average number of resistance phenotypes per isolate was significantly higher for cow compared with poultry. A significant public health concern observed in this study is that multi drug resistant commensal E. Coli strains may constitute a potential reservoir of resistance genes that could be transferred to pathogenic bacteria.    

Thesis Overview

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