Thesis Abstract

Abstract
Photodynamic therapy (PDT) has emerged as a promising treatment modality in the field of dentistry, particularly in the management of periodontal disease. This thesis aimed to assess the efficacy of PDT in the treatment of periodontal disease by conducting a comprehensive review of the existing literature, evaluating the methodology of previous studies, and presenting new findings from a clinical study. The study design involved a randomized controlled trial with a sample size of 100 patients diagnosed with various stages of periodontal disease. The thesis begins with an introduction to the background of PDT in dentistry, highlighting its mechanism of action and potential benefits in periodontal therapy. The problem statement addresses the limitations of current periodontal treatment methods and the need for alternative approaches to achieve optimal outcomes. The objectives of the study include evaluating the clinical efficacy of PDT in reducing periodontal inflammation, improving clinical attachment levels, and enhancing patient-reported outcomes. The literature review encompasses ten key areas, including the pathogenesis of periodontal disease, conventional periodontal treatment modalities, the principles of PDT, and previous clinical studies on PDT in dentistry. The research methodology section outlines the study design, participant recruitment criteria, treatment protocol, outcome measures, and statistical analysis plan. The discussion of findings chapter presents the results of the clinical trial, including changes in clinical parameters such as probing depth, bleeding on probing, and gingival index following PDT treatment. The conclusion and summary chapter summarizes the main findings of the study, discusses the implications for clinical practice, and highlights the strengths and limitations of the research. The significance of this study lies in its contribution to the growing body of evidence supporting the use of PDT as an effective adjunctive therapy for periodontal disease management. Future research directions may focus on optimizing PDT parameters, exploring long-term treatment outcomes, and investigating the cost-effectiveness of PDT compared to traditional periodontal treatments. In conclusion, this thesis provides valuable insights into the efficacy of PDT in the treatment of periodontal disease, offering new perspectives on how this innovative therapy can enhance the overall management of periodontal conditions. The findings of this study may inform clinical decision-making and contribute to the ongoing advancement of periodontal care practices.

Thesis Overview

The project titled "Assessment of the Efficacy of Photodynamic Therapy in the Treatment of Periodontal Disease" aims to investigate the effectiveness of photodynamic therapy (PDT) as a treatment modality for periodontal disease. Periodontal disease is a prevalent oral health condition characterized by inflammation and infection of the gums and supporting structures of the teeth. Traditional treatment methods for periodontal disease include scaling and root planing, antibiotics, and surgical interventions. However, PDT has emerged as a promising alternative therapy that utilizes a photosensitizing agent and light to target and eliminate periodontal pathogens. The research will begin with a comprehensive literature review to explore the existing knowledge and evidence regarding the application of PDT in periodontal therapy. This review will cover the principles of PDT, mechanisms of action, clinical applications, and outcomes reported in previous studies. By synthesizing and analyzing the literature, the research aims to identify gaps, inconsistencies, and areas for further investigation in the field of PDT for periodontal disease. The methodology chapter will outline the research design, participant selection criteria, intervention protocols, outcome measures, and data analysis procedures. The study will involve a clinical trial where patients with periodontal disease will undergo PDT treatment, and their clinical parameters, such as probing depth, clinical attachment level, and gingival inflammation, will be assessed pre- and post-treatment. The research will also explore patient-reported outcomes, adverse effects, and long-term benefits of PDT in comparison to conventional periodontal therapies. The discussion chapter will present and interpret the findings of the study in the context of the existing literature. It will address the efficacy, safety, and feasibility of PDT as a treatment option for periodontal disease and discuss the implications of the results for clinical practice and future research directions. The study aims to contribute valuable insights into the potential role of PDT in improving the outcomes of periodontal therapy and enhancing patient care in the field of dentistry. In conclusion, the project "Assessment of the Efficacy of Photodynamic Therapy in the Treatment of Periodontal Disease" represents a significant contribution to the understanding of PDT as an innovative approach to managing periodontal disease. By evaluating the efficacy of PDT and its impact on clinical outcomes, this research seeks to advance the knowledge and practice of periodontal therapy and promote the development of more effective and minimally invasive treatment strategies for patients with periodontal disease.