Thesis Abstract

Abstract
This thesis presents a comprehensive study on the assessment of the effectiveness of Photodynamic Therapy (PDT) in treating periodontal disease through a clinical investigation. Periodontal disease is a prevalent oral health issue characterized by inflammation of the gums and surrounding tissues, leading to tooth loss if left untreated. PDT is an emerging non-invasive treatment modality that utilizes a photosensitizing agent activated by light to target and eliminate pathogenic bacteria associated with periodontal disease. The study begins with an introduction providing an overview of periodontal disease, current treatment modalities, and the rationale for investigating PDT as a potential alternative therapy. The background of the study delves into the principles of PDT, its mechanism of action, and previous research supporting its efficacy in dental applications. The problem statement highlights the limitations of traditional periodontal treatments and the need for innovative approaches to improve patient outcomes. The objectives of the study are to evaluate the clinical effectiveness of PDT in reducing periodontal inflammation, controlling bacterial growth, and promoting tissue regeneration. The limitations of the study, including sample size constraints and potential confounding variables, are acknowledged to provide a realistic assessment of the research findings. The scope of the study outlines the specific parameters and criteria for patient selection, treatment protocols, and outcome measures. The significance of the study lies in its potential to contribute valuable insights into the utility of PDT as a supplementary or alternative treatment for periodontal disease, offering patients a minimally invasive and potentially more effective therapeutic option. The structure of the thesis is organized into five chapters, including an introduction, literature review, research methodology, discussion of findings, and conclusion. The literature review critically examines existing research on PDT in dentistry, highlighting key studies, methodologies, and outcomes related to its application in periodontal therapy. The research methodology section details the study design, patient recruitment process, treatment protocols, outcome measures, data analysis methods, and ethical considerations. The discussion of findings presents the results of the clinical study, including changes in clinical parameters such as probing depth, clinical attachment level, and gingival inflammation following PDT treatment. The implications of these findings are discussed in relation to the current understanding of periodontal disease management and the potential role of PDT in enhancing treatment outcomes. In conclusion, this thesis provides a comprehensive assessment of the effectiveness of PDT in treating periodontal disease, offering valuable insights into its clinical utility and potential benefits for patients. The study contributes to the growing body of evidence supporting the use of PDT as a promising adjunct therapy in periodontal care, emphasizing its non-invasive nature and targeted antimicrobial effects. Further research is recommended to validate these findings and optimize the integration of PDT into routine periodontal treatment protocols.

Thesis Overview

The project titled "Assessment of the Effectiveness of Photodynamic Therapy in Treating Periodontal Disease: A Clinical Study" aims to investigate the efficacy of photodynamic therapy (PDT) as a treatment modality for periodontal disease. Periodontal disease is a common oral health issue characterized by inflammation and infection of the gums and surrounding tissues, often leading to tooth loss if left untreated. Traditional treatment methods for periodontal disease include scaling and root planing, as well as surgical interventions in severe cases. Photodynamic therapy is a relatively new approach that involves the use of a photosensitizing agent and light of a specific wavelength to target and destroy bacteria and infected tissue in the periodontal pockets. This non-invasive and targeted therapy has shown promising results in the treatment of various dental infections, including periodontal disease. This clinical study will focus on assessing the effectiveness of PDT in treating periodontal disease by evaluating its impact on key clinical parameters such as reduction in pocket depth, clinical attachment level, bleeding on probing, and plaque accumulation. The study will involve a sample of patients diagnosed with periodontal disease who will undergo PDT treatment sessions over a specified period. The research methodology will include a detailed description of the study design, patient selection criteria, treatment protocol, outcome measures, and statistical analysis methods. Data collection will involve clinical examinations, including periodontal probing, and photographic documentation before and after the treatment sessions. The findings of this study will provide valuable insights into the potential of photodynamic therapy as an effective and minimally invasive treatment option for periodontal disease. The results will contribute to the existing body of knowledge on innovative approaches to managing oral health conditions and may have implications for improving treatment outcomes and patient care in the field of dentistry. Overall, this project seeks to advance our understanding of the role of photodynamic therapy in periodontal disease management and offer evidence-based recommendations for its clinical application in dental practice."