Home / Chemistry / Phytochemical analysis and the anti-inflammatory activities of dichloromethane fraction of methhanol extract of crateva adansonii

Phytochemical analysis and the anti-inflammatory activities of dichloromethane fraction of methhanol extract of crateva adansonii

 

Table Of Contents


Chapter ONE

1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms

Chapter TWO

2.1 Overview of Phytochemicals
2.2 Phytochemical Analysis Methods
2.3 Anti-inflammatory Activities in Plants
2.4 Previous Studies on Crateva Adansonii
2.5 Phytochemical Composition of Crateva Adansonii
2.6 Anti-inflammatory Potential of Crateva Adansonii
2.7 Comparison with Other Plant Extracts
2.8 Mechanisms of Action
2.9 Clinical Applications
2.10 Future Research Directions

Chapter THREE

3.1 Research Design
3.2 Selection of Research Approach
3.3 Data Collection Methods
3.4 Sampling Techniques
3.5 Data Analysis Procedures
3.6 Ethical Considerations
3.7 Validity and Reliability
3.8 Limitations of Methodology

Chapter FOUR

4.1 Phytochemical Analysis Results
4.2 Anti-inflammatory Activity Findings
4.3 Comparison with Control Groups
4.4 Statistical Analysis of Results
4.5 Interpretation of Findings
4.6 Discussion on Mechanisms of Action
4.7 Implications for Clinical Practice
4.8 Future Research Recommendations

Chapter FIVE

5.1 Summary of Findings
5.2 Conclusion
5.3 Recommendations for Further Research
5.4 Implications for the Field
5.5 Closing Remarks

Thesis Abstract

Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants (Ryan & Majno, 1983). The urgency generated by increased rate of stroke, atherosclerosis attribute due to prolonged use of cyclooxygenase-1 and Cyclooxygenase- 2 inhibitors have accelerated anti-inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate research (Ryan & Majno, 1983). Attention increasingly has been directed to natural products. These are often more affordable and available and sometimes are perceived as more effective than conventional anti- inflammatory drugs.
Anti-inflammation was carried out using 12 rats which was divided into three groups of 4 rats each. Group 1 and 2 served as the negative and positive control respectively. Group 3 received 25mg/kg b.w. of the dichloromethane fraction of methanol extract of Crateva adansonii showed significance anti-inflammatory activity when compared with the standard difference used.

Thesis Overview

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