Thesis Abstract

Abstract
Osteoarthritis is a common degenerative joint disease affecting dogs, leading to pain, reduced mobility, and decreased quality of life. Stem cell therapy has emerged as a promising treatment modality for osteoarthritis due to its regenerative potential. This thesis aims to assess the efficacy of stem cell therapy in canine osteoarthritis through a comprehensive review of existing literature, research methodology, data analysis, and discussion of findings. Chapter one provides an introduction to the research topic, outlining the background of the study, problem statement, objectives, limitations, scope, significance, and the structure of the thesis. The definitions of key terms related to osteoarthritis and stem cell therapy are also presented to provide clarity and context. Chapter two presents a thorough literature review encompassing ten key aspects related to osteoarthritis in dogs, the mechanisms of action of stem cell therapy, previous studies on stem cell therapy in canine osteoarthritis, and the current state of knowledge in this field. Chapter three details the research methodology employed in this study, including the study design, sample selection, stem cell preparation and administration, outcome measures, data collection methods, statistical analysis, ethical considerations, and potential biases. Chapter four offers an in-depth discussion of the findings obtained from the research, including the evaluation of clinical outcomes, radiographic assessments, histological analyses, and owner-reported improvements post-stem cell therapy in dogs with osteoarthritis. The results are compared to existing literature and discussed in the context of the efficacy of stem cell therapy in canine osteoarthritis. Lastly, chapter five summarizes the key findings of the study, discusses the implications for veterinary practice, suggests areas for further research, and concludes with recommendations for the integration of stem cell therapy into the management of canine osteoarthritis. Overall, this thesis contributes to the growing body of knowledge on the use of stem cell therapy as a potential treatment option for canine osteoarthritis, highlighting its efficacy, safety, and future prospects in veterinary medicine.

Thesis Overview

The project titled "Assessment of the Efficacy of Stem Cell Therapy in Canine Osteoarthritis" aims to investigate the potential benefits and effectiveness of using stem cell therapy as a treatment option for canine osteoarthritis. Osteoarthritis is a common degenerative joint disease in dogs, leading to pain, stiffness, and reduced mobility. Current treatment options for osteoarthritis in dogs are limited and often focus on managing symptoms rather than addressing the underlying cause of the disease. Stem cell therapy has emerged as a promising regenerative medicine approach that harnesses the regenerative potential of stem cells to promote tissue repair and regeneration. In the context of osteoarthritis, stem cell therapy holds the potential to repair damaged joint tissues, reduce inflammation, and improve joint function in affected dogs. This research project will involve conducting a comprehensive literature review to explore the existing knowledge and research findings related to stem cell therapy for osteoarthritis in dogs. The review will include an analysis of studies investigating the mechanisms of action of stem cells in joint repair, the types of stem cells used, the methods of delivery, and the reported outcomes in canine patients. In addition to the literature review, the project will include a research methodology section outlining the experimental design, sample population, stem cell source, administration protocol, outcome measures, and statistical analysis plan. The study aims to evaluate the efficacy of stem cell therapy in improving clinical symptoms, joint function, and quality of life in dogs with osteoarthritis. Furthermore, the project will present a detailed discussion of the findings, including the interpretation of results, comparison with existing literature, limitations of the study, and implications for future research and clinical practice. The discussion will also address any challenges encountered during the study and provide recommendations for optimizing the use of stem cell therapy in canine osteoarthritis management. Overall, this research project seeks to contribute valuable insights into the potential benefits and limitations of stem cell therapy as a novel treatment approach for canine osteoarthritis. By evaluating the efficacy of stem cell therapy in improving clinical outcomes in dogs with osteoarthritis, this study aims to advance our understanding of regenerative medicine applications in veterinary orthopedics and provide evidence-based recommendations for the use of stem cell therapy in clinical practice."