Thesis Abstract

Abstract
This thesis investigates the potential application of stem cell therapy in the treatment of canine osteoarthritis. Osteoarthritis is a common degenerative joint disease in dogs, causing pain, inflammation, and reduced mobility. Current treatment options have limitations, leading to a growing interest in regenerative medicine approaches such as stem cell therapy. The objective of this study is to explore the efficacy and safety of utilizing stem cell therapy as a novel treatment modality for canine osteoarthritis. The research methodology involved an extensive literature review to examine the existing knowledge on stem cell therapy and its application in veterinary medicine. Ten key themes emerged from the literature review, highlighting the mechanisms of action, types of stem cells used, administration routes, outcomes, and challenges associated with stem cell therapy for osteoarthritis in dogs. In the investigation of stem cell therapy for treating canine osteoarthritis, the study employed a range of research methodologies, including in vitro studies, in vivo animal models, and clinical trials. The findings of these studies were analyzed and synthesized to provide a comprehensive understanding of the potential benefits and limitations of stem cell therapy in canine osteoarthritis treatment. The results of this research reveal promising outcomes in terms of pain relief, improved joint function, and cartilage regeneration following stem cell therapy in dogs with osteoarthritis. However, challenges such as variability in treatment response, optimal dosing regimens, and long-term safety considerations were also identified. In conclusion, this thesis underscores the potential of stem cell therapy as a promising treatment option for canine osteoarthritis. The findings contribute to the growing body of evidence supporting the use of regenerative medicine in veterinary orthopedics. Further research is warranted to address the remaining gaps in knowledge and optimize the clinical application of stem cell therapy for the management of osteoarthritis in dogs.

Thesis Overview

Overview: The research project titled "Exploring the Use of Stem Cell Therapy in Treating Canine Osteoarthritis" aims to investigate the potential applications of stem cell therapy in managing osteoarthritis in dogs. Osteoarthritis is a common degenerative joint disease that affects dogs of all ages, leading to pain, reduced mobility, and decreased quality of life. Current treatment options for canine osteoarthritis are limited and often focus on symptom management rather than addressing the underlying cause of the disease. Stem cell therapy has emerged as a promising alternative approach for treating osteoarthritis in both humans and animals. Stem cells have the unique ability to differentiate into various cell types, repair damaged tissues, and modulate the inflammatory response associated with osteoarthritis. By harnessing the regenerative potential of stem cells, it is possible to promote tissue repair, reduce inflammation, and alleviate pain in arthritic joints. This research project will delve into the mechanisms of action of stem cell therapy in treating canine osteoarthritis, exploring how stem cells interact with the joint environment, promote tissue regeneration, and modulate the immune response. The study will also investigate the safety, efficacy, and long-term outcomes of stem cell therapy in canine patients with osteoarthritis. Through a comprehensive review of existing literature, analysis of clinical studies, and possibly experimental research, this project aims to provide valuable insights into the potential benefits and limitations of stem cell therapy for managing osteoarthritis in dogs. By shedding light on the underlying science and clinical applications of stem cell therapy, this research has the potential to contribute to the development of innovative and more effective treatment strategies for canine osteoarthritis. Overall, this research project seeks to advance our understanding of stem cell therapy as a novel approach to treating canine osteoarthritis, with the ultimate goal of improving the quality of life and overall well-being of dogs suffering from this debilitating joint disease.