Thesis Abstract

Abstract
Osteoarthritis is a common degenerative joint disease in dogs that can significantly impact their quality of life. Traditional treatment options such as medication and surgery have limitations in providing long-term relief. Stem cell therapy has emerged as a promising alternative for managing osteoarthritis by promoting tissue regeneration and reducing inflammation. This thesis investigates the efficacy of stem cell therapy in treating osteoarthritis in dogs, aiming to evaluate its effectiveness and safety as a treatment modality. The study begins with an introduction to the background of osteoarthritis in dogs, highlighting the prevalence and impact of the disease on canine health. The problem statement underscores the limitations of current treatment options and the need for more effective therapies. The objectives of the study include assessing the clinical outcomes of stem cell therapy in dogs with osteoarthritis and investigating the mechanisms of action involved in the treatment process. A comprehensive literature review examines existing research on stem cell therapy for osteoarthritis in dogs, focusing on key findings and gaps in the current knowledge. The methodology section outlines the research design, sample selection criteria, stem cell administration protocols, outcome measures, and statistical analysis methods employed in the study. The results of the study are presented in the discussion chapter, detailing the clinical improvements observed in dogs following stem cell therapy. Factors such as pain reduction, improved joint function, and histological changes in the affected joints are analyzed to assess the overall efficacy of the treatment. The findings are discussed in relation to previous studies and the potential implications for future research and clinical practice. In conclusion, this thesis provides valuable insights into the efficacy of stem cell therapy in treating osteoarthritis in dogs. The results demonstrate promising outcomes in terms of pain relief and functional improvement, supporting the use of stem cell therapy as a viable treatment option for canine osteoarthritis. The limitations of the study and areas for further investigation are also discussed, highlighting the need for continued research to optimize the use of stem cell therapy in veterinary medicine. Keywords osteoarthritis, dogs, stem cell therapy, efficacy, treatment, regenerative medicine, joint disease, canine health.

Thesis Overview

The project titled "Investigating the efficacy of stem cell therapy in treating osteoarthritis in dogs" focuses on exploring the potential of stem cell therapy as a treatment option for osteoarthritis in canines. Osteoarthritis is a common degenerative joint disease in dogs, causing pain, stiffness, and reduced mobility. Traditional treatments for osteoarthritis in dogs often provide limited relief and may not address the underlying causes of the disease. Stem cell therapy has emerged as a promising regenerative medicine approach that harnesses the regenerative potential of stem cells to repair damaged tissues and promote healing. In the context of osteoarthritis, stem cell therapy offers the potential to regenerate cartilage, reduce inflammation, and alleviate pain, thus providing a more effective and long-lasting treatment option for affected dogs. This research overview will delve into the current understanding of osteoarthritis in dogs, the principles of stem cell therapy, and the existing evidence supporting the use of stem cell therapy in veterinary medicine. The project will investigate the efficacy of stem cell therapy in treating osteoarthritis in dogs through a comprehensive review of existing studies, experimental research, and clinical trials. The study will involve evaluating the outcomes of stem cell therapy in dogs with naturally occurring osteoarthritis, assessing improvements in pain levels, joint function, and overall quality of life. By examining the mechanisms of action of stem cells in promoting tissue repair and regeneration, the project aims to gain insights into the therapeutic potential of stem cell therapy for osteoarthritis in dogs. Furthermore, the research will explore the safety, feasibility, and long-term effects of stem cell therapy in canine patients, addressing concerns related to immunogenicity, tumorigenicity, and potential adverse reactions. Through a multidisciplinary approach combining veterinary medicine, regenerative biology, and translational research, this project seeks to advance our understanding of stem cell therapy as a viable treatment option for osteoarthritis in dogs. Overall, this research overview sets the stage for a comprehensive investigation into the efficacy of stem cell therapy in managing osteoarthritis in dogs, with the ultimate goal of improving the quality of life and well-being of canine patients suffering from this debilitating condition.