Thesis Abstract

Abstract
Osteoarthritis is a common degenerative joint disease that affects both humans and animals, including dogs. The use of stem cell therapy as a potential treatment for osteoarthritis in dogs has gained significant attention in recent years. This thesis aims to investigate the effectiveness of stem cell therapy in treating osteoarthritis in dogs through a comprehensive review of existing literature, research methodology, and discussion of findings. Chapter one provides an introduction to the research topic, outlining the background of the study, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of key terms. The literature review in chapter two examines ten key studies related to stem cell therapy for osteoarthritis in dogs, highlighting the current understanding of the topic and identifying gaps in knowledge. Chapter three details the research methodology, including the selection of study subjects, stem cell isolation and administration protocols, evaluation criteria for treatment efficacy, and statistical analysis methods. The chapter also discusses ethical considerations and potential challenges encountered during the research process. In chapter four, the findings of the study are presented and analyzed in detail. The outcomes of stem cell therapy in treating osteoarthritis in dogs are discussed, including improvements in clinical symptoms, joint function, and quality of life. The chapter also addresses any limitations of the study and suggests areas for further research. Finally, chapter five offers a conclusion and summary of the thesis, highlighting the key findings, implications for veterinary practice, and recommendations for future research. The results of this study contribute to the growing body of evidence supporting the use of stem cell therapy as a promising treatment option for osteoarthritis in dogs, with the potential to improve the quality of life for canine patients suffering from this debilitating condition.

Thesis Overview

The project titled "Investigation of the Use of Stem Cell Therapy in Treating Osteoarthritis in Dogs" aims to explore the potential of stem cell therapy as a novel treatment approach for osteoarthritis in dogs. Osteoarthritis is a common degenerative joint disease characterized by progressive cartilage loss, inflammation, and pain, affecting the quality of life of affected dogs. This research overview will delve into the background of osteoarthritis in dogs, highlighting its prevalence, clinical manifestations, and current treatment options. It will discuss the limitations of conventional therapies, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and physical therapy, which focus on symptom management rather than disease modification. The focus of this project is to investigate the use of stem cell therapy as a regenerative medicine approach to address the underlying pathology of osteoarthritis in dogs. Stem cells have the unique ability to differentiate into various cell types, including cartilage, and possess anti-inflammatory and immunomodulatory properties, making them promising candidates for osteoarthritis treatment. The research methodology will involve a comprehensive literature review to evaluate the existing evidence on the efficacy and safety of stem cell therapy in treating osteoarthritis in dogs. This will include studies on stem cell sources, administration routes, dosages, and outcomes in canine osteoarthritis models. Additionally, the project will explore the mechanisms of action of stem cells in promoting cartilage repair and reducing inflammation in arthritic joints. The study will also address the practical aspects of implementing stem cell therapy in veterinary clinical practice, such as regulatory considerations, cost-effectiveness, and ethical implications. Furthermore, the project will assess the long-term benefits and potential risks associated with stem cell treatment in dogs with osteoarthritis. The significance of this research lies in its potential to advance the field of veterinary regenerative medicine and provide new insights into the management of osteoarthritis in dogs. By elucidating the therapeutic mechanisms and clinical outcomes of stem cell therapy, this project has the potential to pave the way for innovative treatment strategies that offer disease-modifying effects and improved quality of life for canine patients with osteoarthritis. In conclusion, the investigation of the use of stem cell therapy in treating osteoarthritis in dogs represents a critical step towards developing more effective and sustainable treatment options for this debilitating joint disease. Through rigorous scientific inquiry and translational research, this project aims to contribute valuable knowledge to the field of veterinary medicine and ultimately improve the well-being of dogs suffering from osteoarthritis.