Thesis Abstract

Abstract
This thesis investigates the potential benefits and challenges associated with utilizing stem cell therapy for the treatment of canine osteoarthritis. Osteoarthritis is a common degenerative joint disease affecting dogs, leading to pain, reduced mobility, and decreased quality of life. In recent years, stem cell therapy has emerged as a promising approach for treating osteoarthritis in both humans and animals. This study aims to explore the effectiveness, safety, and feasibility of stem cell therapy in canine osteoarthritis, focusing on understanding the underlying mechanisms, evaluating clinical outcomes, and identifying key factors influencing treatment success. The research begins with a comprehensive review of the literature, examining studies related to stem cell therapy in veterinary medicine, osteoarthritis pathophysiology, and current treatment options for canine osteoarthritis. The literature review highlights the gaps in existing knowledge and sets the foundation for the subsequent research phases. Methodologically, this study employs a mixed-methods approach, integrating both quantitative and qualitative research methods. The quantitative aspect involves a retrospective analysis of clinical data from canine patients treated with stem cell therapy for osteoarthritis. Key outcome measures include pain scores, joint function, radiographic assessments, and owner satisfaction levels. The qualitative component comprises interviews with veterinarians, pet owners, and stem cell therapy providers to gather insights on treatment experiences, challenges, and perceptions. The findings from the research methodology section are synthesized and discussed in chapter four, where the effectiveness and limitations of stem cell therapy in treating canine osteoarthritis are critically evaluated. Factors influencing treatment outcomes, such as patient selection, stem cell source, delivery methods, and post-treatment care, are analyzed to provide practical recommendations for optimizing treatment protocols. In conclusion, this thesis underscores the potential of stem cell therapy as a valuable treatment option for canine osteoarthritis, offering a novel approach to managing this prevalent condition in veterinary practice. By addressing the gaps in current knowledge and presenting evidence-based insights, this study contributes to advancing the field of regenerative medicine in veterinary orthopedics and underscores the importance of further research to enhance the efficacy and accessibility of stem cell therapy for canine patients with osteoarthritis.

Thesis Overview