Home / Pharmacy / ESTIMATION OF THE EFFECT OF CISAMPELOUS OWANRENSIS BENZENE FRACTION ON GLUCOSE ABSORPTION ACROSS THE INTESTINAL EPITHELIUM OF WISTER RATS ON ALOXAN INDUCED DIABETES

ESTIMATION OF THE EFFECT OF CISAMPELOUS OWANRENSIS BENZENE FRACTION ON GLUCOSE ABSORPTION ACROSS THE INTESTINAL EPITHELIUM OF WISTER RATS ON ALOXAN INDUCED DIABETES

 

Table Of Contents


<p>Title page &nbsp; — &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – i &nbsp; <br><br>Declaration — &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; -ii<br><br>Approval page — – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; -iii<br><br>Dedication — &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; -iv<br><br>Acknowledgement — &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; -v &nbsp; <br><br>Table of content — &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; -vi &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Abstract — – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; – &nbsp; &nbsp; &nbsp; -vii<br></p>

Thesis Abstract

<p>Diabetes is a global public health crisis that threatens the economies of all nations, particularly developing countries. It is generally characterized by hyperglycaemia and hyperlipidaemia culminating in severe morbidities. This study aimed to assess the effects of Cissampelos owanrensis on glucose absorption in alloxan-induced diabetic male Wistar rats. Twenty (20) adult Wistar rats were divided into four (4) groups of five rats each (n=5). Groups 1 and 2 served as the control groups and group 3 and 4 were induced with diabetes by an intraperitoneal injection of alloxan (40mg/kg). The normoglycaemic groups (1 and 2) and the alloxan-induced diabetic groups (3 and 4) were treated with 300mg/kg of Cissampelos owanrensis. The fasting glucose level of the animals was monitored at 1 hour, 3 hours and 4 hours. At the end of the experiment the rats were sacrificed by cervical dislocation, blood samples were centrifuged to obtain the serum for biochemical analysis. The duodenum, jejunum and ileum were excised for biochemical study. Data obtained were analyzed using SPSS statistical tool and expressed as mean±SEM. Results show that fasting blood glucose levels of diabetic rats was reduced significantly on administration of 300mg/kg of the plant extract(502.33±5.57 after 1 hour, 427.33±7.67 after 3 hours, 298.33±10.91 after 4 hours). In conclusion, benzene fractions of Cissampelos owanrensis demonstrated significant reduction in glucose absorption across the intestinal epithelium.<br><br><br></p>

Thesis Overview

Blazingprojects Mobile App

📚 Over 50,000 Project Materials
📱 100% Offline: No internet needed
📝 Over 98 Departments
🔍 Project Journal Publishing
🎓 Undergraduate/Postgraduate
📥 Instant Whatsapp/Email Delivery

Blazingprojects App

Related Research

Pharmacy. 2 min read

Development of novel drug delivery systems for targeted cancer therapy...

The project titled "Development of novel drug delivery systems for targeted cancer therapy" focuses on the critical need to improve cancer treatment e...

BP
Blazingprojects
Read more →
Pharmacy. 2 min read

Development of Novel Drug Delivery Systems for Targeted Cancer Therapy...

The project titled "Development of Novel Drug Delivery Systems for Targeted Cancer Therapy" aims to address the urgent need for more effective and tar...

BP
Blazingprojects
Read more →
Pharmacy. 2 min read

Development of Novel Drug Delivery Systems for Targeted Cancer Therapy...

The project titled "Development of Novel Drug Delivery Systems for Targeted Cancer Therapy" aims to address the critical need for more effective and e...

BP
Blazingprojects
Read more →
Pharmacy. 4 min read

Development of Novel Drug Delivery Systems for Targeted Cancer Therapy...

The project titled "Development of Novel Drug Delivery Systems for Targeted Cancer Therapy" aims to address the pressing need for more effective and t...

BP
Blazingprojects
Read more →
Pharmacy. 4 min read

Development and Evaluation of Novel Drug Delivery Systems for Targeted Cancer Therap...

The project titled "Development and Evaluation of Novel Drug Delivery Systems for Targeted Cancer Therapy" aims to address the growing need for more e...

BP
Blazingprojects
Read more →
Pharmacy. 3 min read

Development of Novel Drug Delivery Systems for Targeted Cancer Therapy...

The project titled "Development of Novel Drug Delivery Systems for Targeted Cancer Therapy" aims to address the critical need for more effective and t...

BP
Blazingprojects
Read more →
Pharmacy. 2 min read

Development of Novel Drug Delivery Systems for Targeted Cancer Therapy...

The project titled "Development of Novel Drug Delivery Systems for Targeted Cancer Therapy" focuses on addressing the challenges associated with conve...

BP
Blazingprojects
Read more →
Pharmacy. 2 min read

Development of a Novel Drug Delivery System for Targeted Cancer Therapy...

The research project titled "Development of a Novel Drug Delivery System for Targeted Cancer Therapy" aims to address the critical need for more effec...

BP
Blazingprojects
Read more →
Pharmacy. 4 min read

Development and Evaluation of Novel Drug Delivery Systems for Targeted Cancer Therap...

The project titled "Development and Evaluation of Novel Drug Delivery Systems for Targeted Cancer Therapy" aims to address the critical need for innov...

BP
Blazingprojects
Read more →
WhatsApp Click here to chat with us