Thesis Abstract

Abstract
The development of novel drug delivery systems for targeted cancer therapy is a significant area of research aimed at improving the efficacy and safety of cancer treatment. This thesis focuses on the design, development, and evaluation of innovative drug delivery systems that can specifically target cancer cells while minimizing toxicity to healthy tissues. The use of targeted drug delivery systems offers the potential to enhance the therapeutic outcomes of anticancer agents, reduce side effects, and improve patient quality of life. Chapter 1 provides an introduction to the research topic, presenting the background of the study, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of key terms. The literature review in Chapter 2 critically analyzes existing research on drug delivery systems for cancer therapy, highlighting the strengths and limitations of current approaches. Chapter 3 details the research methodology employed in this study, including the selection of materials, synthesis methods, characterization techniques, and in vitro and in vivo evaluation of the developed drug delivery systems. The methodology section also discusses ethical considerations and potential challenges encountered during the research process. In Chapter 4, the findings of the study are presented and discussed in detail. The efficacy, specificity, and safety of the novel drug delivery systems are evaluated based on in vitro and in vivo experiments. The results demonstrate the potential of the developed systems to effectively deliver anticancer drugs to target cells and inhibit tumor growth, with minimal off-target effects. Chapter 5 concludes the thesis by summarizing the key findings, discussing their implications for cancer therapy, and suggesting future research directions. The conclusion emphasizes the importance of continued innovation in drug delivery systems to overcome current challenges in cancer treatment and improve patient outcomes. Overall, this thesis contributes to the field of cancer therapy by proposing novel drug delivery systems that have the potential to revolutionize the way cancer is treated. By targeting cancer cells specifically, these innovative systems offer promising prospects for enhancing the efficacy and safety of anticancer drugs, ultimately improving patient outcomes and quality of life.

Thesis Overview

The project titled "Development of Novel Drug Delivery Systems for Targeted Cancer Therapy" aims to address the challenge of effectively targeting cancer cells while minimizing side effects on healthy tissues. Cancer therapy often involves the use of chemotherapy drugs, which can have toxic effects on the body due to their non-specific nature. Therefore, the development of novel drug delivery systems that can specifically target cancer cells is crucial for improving the efficacy and safety of cancer treatment. This research project will focus on exploring and developing innovative drug delivery systems that can deliver anti-cancer drugs directly to cancer cells, while sparing healthy tissues. Various drug delivery approaches, such as nanoparticles, liposomes, micelles, and antibody-drug conjugates, will be investigated for their potential in targeted cancer therapy. The project will also involve the synthesis and characterization of these drug delivery systems to optimize their drug loading capacity, stability, and targeting specificity. Furthermore, the project will evaluate the in vitro and in vivo efficacy of the developed drug delivery systems using cancer cell lines and animal models. The research will aim to assess the cytotoxicity, cellular uptake, and anti-tumor activity of the drug-loaded delivery systems to determine their therapeutic potential in cancer treatment. Additionally, the project will investigate the pharmacokinetics and biodistribution of the drug delivery systems to understand their behavior in the body and optimize their dosing regimens. Overall, this research work on the development of novel drug delivery systems for targeted cancer therapy holds significant promise in revolutionizing cancer treatment by enhancing the precision and effectiveness of anti-cancer drugs while minimizing undesirable side effects. The findings of this study have the potential to contribute to the advancement of personalized and targeted approaches in cancer therapy, ultimately improving patient outcomes and quality of life.