Thesis Abstract

Abstract
Cancer remains a significant global health challenge, necessitating the continuous exploration of innovative treatment strategies. This thesis focuses on the development and evaluation of novel drug delivery systems tailored for targeted cancer therapy. The objective of this research is to address the limitations of current cancer treatment approaches by designing effective drug delivery systems that enhance the specificity and efficacy of anticancer agents while minimizing off-target effects. Chapter 1 provides a comprehensive introduction to the research study, presenting the background of the study, the problem statement, research objectives, limitations, scope, significance, structure of the thesis, and definition of key terms. The literature review in Chapter 2 synthesizes existing knowledge on drug delivery systems for cancer therapy, covering topics such as nanoparticles, liposomes, micelles, and antibody-drug conjugates, among others. Chapter 3 details the research methodology employed in this study, including the selection of materials, formulation development, characterization techniques, in vitro and in vivo evaluation methods, and statistical analysis. The results of the study are discussed in Chapter 4, highlighting the key findings related to the design, characterization, and efficacy of the novel drug delivery systems in targeting cancer cells. The conclusion and summary in Chapter 5 summarize the research findings, discuss the implications of the results, and propose recommendations for future research directions in the field of targeted cancer therapy. Overall, this thesis contributes to the advancement of drug delivery systems for cancer treatment, offering promising avenues for the development of more effective and personalized therapeutic approaches in the fight against cancer.

Thesis Overview

The project titled "Development and Evaluation of Novel Drug Delivery Systems for Targeted Cancer Therapy" aims to address the critical need for more effective and targeted treatment options for cancer patients. Cancer remains one of the leading causes of mortality worldwide, and developing innovative drug delivery systems is essential for improving therapeutic outcomes and reducing side effects associated with conventional cancer treatments. This research project will focus on the development and evaluation of novel drug delivery systems specifically designed for targeted cancer therapy. The primary objective is to enhance the efficacy of anticancer drugs while minimizing their systemic toxicity. By utilizing advanced drug delivery technologies, such as nanoparticles, liposomes, and micelles, the project seeks to improve drug bioavailability, prolong circulation time, and achieve targeted delivery to cancer cells. The project will begin with a comprehensive literature review to establish the current state of drug delivery systems in cancer therapy. This review will explore various types of drug carriers, their mechanisms of action, and their applications in cancer treatment. By examining existing research findings and gaps in the field, the project aims to identify opportunities for developing more advanced and efficient drug delivery systems. Following the literature review, the research methodology will involve the design and synthesis of novel drug delivery systems tailored for targeted cancer therapy. This will include the selection of appropriate drug carriers, optimization of drug loading methods, and evaluation of the physicochemical properties of the drug delivery systems. In vitro and in vivo studies will be conducted to assess the efficacy, safety, and targeting capabilities of the developed drug carriers. The findings of this research project are expected to contribute significantly to the field of cancer therapy by providing valuable insights into the design and evaluation of advanced drug delivery systems for targeted cancer treatment. By enhancing the specificity and effectiveness of anticancer drugs, these novel drug delivery systems have the potential to revolutionize cancer treatment strategies and improve patient outcomes. In conclusion, the project on the "Development and Evaluation of Novel Drug Delivery Systems for Targeted Cancer Therapy" represents a crucial step towards advancing the field of cancer drug delivery and personalized medicine. Through innovative research and interdisciplinary collaboration, this project aims to develop cutting-edge drug delivery technologies that can revolutionize cancer treatment and benefit patients worldwide.