Thesis Abstract

Abstract
Cancer remains one of the most challenging diseases affecting millions of people worldwide. Conventional cancer treatment methods such as chemotherapy often present limitations in terms of efficacy and adverse side effects. The development of novel drug delivery systems has emerged as a promising approach to enhance the effectiveness of cancer treatment while minimizing systemic toxicity. This thesis focuses on the development and evaluation of innovative drug delivery systems tailored for cancer treatment. Chapter One provides an introduction to the study, highlighting the background of the research, the problem statement, research objectives, limitations, scope, significance of the study, structure of the thesis, and key definitions of terms. The literature review in Chapter Two encompasses ten critical aspects related to drug delivery systems, cancer treatment, nanotechnology, targeted therapy, and biocompatible materials, among others. Chapter Three delves into the research methodology with a detailed explanation of the research design, sample selection, data collection methods, experimental procedures, analysis techniques, ethical considerations, and limitations. This chapter aims to provide a comprehensive overview of the methodology employed in designing and evaluating the novel drug delivery systems. The findings of the research are extensively discussed in Chapter Four, focusing on the performance, efficiency, biocompatibility, and targeted delivery capabilities of the developed drug delivery systems. The results are analyzed in relation to existing literature and current trends in cancer treatment, highlighting the potential impact of these novel systems on improving patient outcomes and quality of life. Finally, Chapter Five presents the conclusion and summary of the thesis, emphasizing the key findings, implications for future research, practical applications, and recommendations for further development and evaluation of drug delivery systems for cancer treatment. Overall, this thesis contributes to the growing body of knowledge in the field of oncology and drug delivery, offering valuable insights into the potential of innovative approaches to enhance cancer therapy. In conclusion, the research conducted in this thesis underscores the importance of continuous innovation and evaluation of drug delivery systems for cancer treatment. The development of novel approaches holds significant promise in improving treatment outcomes, reducing side effects, and enhancing patient well-being in the fight against cancer.

Thesis Overview

The project titled "Development and Evaluation of Novel Drug Delivery Systems for Cancer Treatment" aims to address the critical need for innovative drug delivery systems to enhance the efficacy and reduce the side effects of cancer treatments. Cancer remains one of the leading causes of death worldwide, and the development of novel drug delivery systems holds great promise in improving patient outcomes. The research will begin with a comprehensive review of existing literature on drug delivery systems for cancer treatment. This review will cover various types of drug delivery systems, including nanoparticles, liposomes, micelles, and hydrogels, highlighting their advantages and limitations in delivering anticancer agents. Following the literature review, the research will focus on the design and development of novel drug delivery systems specifically tailored for cancer treatment. This will involve the formulation of drug-loaded nanoparticles or other carriers that can effectively target cancer cells while minimizing off-target effects on healthy tissues. Various parameters such as particle size, surface charge, and drug release kinetics will be optimized to ensure the efficacy of the delivery system. The evaluation of these novel drug delivery systems will be conducted through in vitro and in vivo studies. In vitro experiments will assess the cellular uptake, cytotoxicity, and drug release profiles of the developed formulations using cancer cell lines. Subsequently, in vivo studies will be performed to evaluate the pharmacokinetics, biodistribution, and therapeutic efficacy of the drug delivery systems in animal models of cancer. The findings from these studies will be critically analyzed and discussed in the context of existing literature, highlighting the potential of the novel drug delivery systems in improving cancer treatment outcomes. The project will also address the challenges and limitations encountered during the development and evaluation of these systems, providing insights for future research directions. In conclusion, the research on the development and evaluation of novel drug delivery systems for cancer treatment represents a crucial step towards enhancing the effectiveness of anticancer therapies while minimizing adverse effects. The project aims to contribute valuable knowledge to the field of cancer drug delivery and ultimately improve patient outcomes in the fight against cancer.