Thesis Abstract

Abstract
The field of oncology has witnessed significant advancements in recent years with the development of targeted drug delivery systems for cancer therapy. This thesis focuses on the development of novel drug delivery systems tailored specifically for targeted cancer therapy. The aim of this research is to address the limitations of traditional cancer treatments by enhancing drug delivery efficiency, reducing systemic toxicity, and improving overall therapeutic outcomes. The introductory chapter provides a comprehensive overview of the background of the study, problem statement, objectives, limitations, scope, significance, structure of the thesis, and definition of key terms. The literature review chapter encompasses ten critical areas related to targeted drug delivery systems, including nanotechnology, antibody-drug conjugates, liposomes, and polymer-based drug carriers, among others. The research methodology chapter outlines the methodology employed in this study, including the selection of drug delivery systems, in vitro and in vivo experiments, data collection, and analysis techniques. The chapter also discusses the ethical considerations and limitations of the research methodology. The findings chapter presents a detailed discussion of the results obtained from the experiments conducted in this study. The discussion covers the efficacy of the novel drug delivery systems in targeting cancer cells, the mechanisms of action, drug release profiles, and potential therapeutic applications. In conclusion, this thesis provides valuable insights into the development of novel drug delivery systems for targeted cancer therapy. The research findings highlight the potential of these systems to revolutionize cancer treatment by improving drug efficacy, reducing side effects, and enhancing patient outcomes. This study contributes to the growing body of knowledge in the field of oncology and lays the groundwork for future research in the development of innovative cancer therapies. Keywords Drug delivery systems, targeted therapy, cancer treatment, nanotechnology, polymer-based carriers, therapeutic outcomes.

Thesis Overview

The research project titled "Development of Novel Drug Delivery Systems for Targeted Cancer Therapy" focuses on the design and implementation of innovative drug delivery systems specifically tailored for the treatment of cancer. Cancer remains one of the most challenging diseases to treat, and conventional chemotherapy often lacks specificity, leading to significant side effects and limited efficacy. Therefore, the development of targeted drug delivery systems represents a promising approach to enhance the therapeutic outcomes while minimizing adverse effects. This research aims to address the limitations of current cancer treatment modalities by developing novel drug delivery systems that can target cancer cells more effectively. By utilizing advanced nanotechnology and bioengineering principles, the project seeks to design drug carriers that can deliver therapeutic agents directly to cancer cells, sparing healthy tissues from damage. The targeted drug delivery systems will be designed to enhance drug stability, circulation time, and cellular uptake, thereby improving the overall treatment efficacy. The project will involve a comprehensive literature review to analyze existing drug delivery strategies and identify key challenges and opportunities in the field. Subsequently, the research methodology will encompass the design and synthesis of novel drug carriers, as well as in vitro and in vivo evaluation of their targeting efficiency and therapeutic efficacy. The study will also investigate the pharmacokinetics and biodistribution of the drug delivery systems to assess their safety profile and potential for clinical translation. The findings of this research are expected to contribute significantly to the field of cancer therapy by providing insights into the design and optimization of targeted drug delivery systems. The development of more efficient and selective drug carriers has the potential to revolutionize cancer treatment, offering patients better outcomes and improved quality of life. Ultimately, the project aims to bridge the gap between bench research and clinical application, paving the way for the development of personalized and precision medicine approaches for cancer therapy.