Thesis Abstract

Abstract
Mistletoe is a parasitic plant known for its various medicinal properties and traditional uses in different cultures. This study aimed to investigate the phytochemical composition and antimicrobial activity of mistletoe leaves. The phytochemical analysis revealed the presence of various bioactive compounds such as alkaloids, flavonoids, tannins, saponins, and phenols in the mistletoe leaf extract. These compounds have been reported to exhibit a wide range of pharmacological activities including antimicrobial properties. The antimicrobial activity of mistletoe leaf extract was evaluated against a panel of pathogenic microorganisms including bacteria and fungi. The results showed significant antimicrobial activity of the mistletoe extract against both Gram-positive and Gram-negative bacteria as well as fungal strains. The antimicrobial activity was attributed to the presence of bioactive compounds such as alkaloids and phenolic compounds in the mistletoe leaf extract. Furthermore, the study also investigated the potential synergistic effects of mistletoe leaf extract in combination with conventional antibiotics. The results revealed that the combination of mistletoe leaf extract with antibiotics enhanced the antimicrobial activity against various pathogens compared to the individual treatments. This suggests that mistletoe leaf extract may have the potential to be used as an adjuvant therapy in combination with antibiotics to combat microbial infections. Overall, the findings of this study provide valuable insights into the phytochemical composition and antimicrobial activity of mistletoe leaves. The presence of bioactive compounds in the mistletoe leaf extract and its significant antimicrobial effects against a range of pathogens highlight the therapeutic potential of mistletoe as a natural antimicrobial agent. Further research is warranted to explore the mechanisms of action of mistletoe leaf extract against microbial pathogens and to evaluate its potential applications in the development of novel antimicrobial agents.

Thesis Overview

The sample of Mistletoe leaves was collected from an orange tree at Ururo in Umunze Anambra State. The leaves was extracted by using some solvent like ethanolic solvent, aqueous solvent n-hexane solvent and ethyl acetate solvent. The extracts was further analyzed which helps in determining the presence of phytochemical compounds in the Mistletoe plant leaf, such as alkaloids, flavonoid, phenol, tannins, steroid and saponins. These phytochemical compounds are found to be antimicrobial active agents. Mystetoe Leaves

The efficiency of this plant in the treatment of various diseases necessitated the present work in order to identify the classes of natural products present in the leaf of the plant. These pharmacological values of this plant in herbal medicine and as base for the development of new drug. Mystetoe Leaves