Cover page i
Dedication ii
Acknowledgement iii
Tables of Content iv
Abstract vi
1.0
2.0
3.0
4.0
Introduction:
N-acylated aromatic amines (those having an acyl group, RCO- substituted on nitrogen) are important in over-the-counter headache remedies. Over-the-counter drugs are those you may buy without a prescription. Acetanilide, phenacetin, and acetaminophen are mild analgesics and antipyretics and are important, along with aspirin, in many non-prescription drugs.
The discovery that acetanilide was an effective antipyretic came about by accident in 1886. At the University of Strassburg, Professor Kussmaul, of the Department of Internal Medicine, asked two assistants to give naphthalene as a treatment for intestinal worms. Cahn and Hepp, who had been testing naphthalene as a possible vermifuge (an agent that expels worms) by accident, mixed up a bottle of acetanilide and the bottle of naphthalene. The patientβs worms didnβt disappear but his fever did β dramatically. In another instance of serendipity, it was soon in production and remained in use for several years because it was so cheap to produce. However, it had a serious side effect involving the deactivation of some of the hemoglobin in red blood cells. However, restrictions have been placed on its use due to kidney damage in long-term users. The publication of Cahn and Hepp describing their experiments with acetanilide caught the attention of Carl Duisberg, director of research at the Bayer Company in Germany. Duisberg was confronted
π Over 50,000 Research Thesis
π± 100% Offline: No internet needed
π Over 98 Departments
π Thesis-to-Journal Publication
π Undergraduate/Postgraduate Thesis
π₯ Instant Whatsapp/Email Delivery
The project titled "Development of a Novel Process for the Sustainable Production of Biofuels from Algae" aims to address the pressing need for sustai...
The project "Optimization of Biofuel Production from Algae Biomass Using Supercritical Fluid Extraction" aims to explore a sustainable and efficient m...
The project titled "Optimization of Reaction Conditions for Biodiesel Production Using Heterogeneous Catalysts" aims to address the growing demand for...
The project titled "Optimization of a Hydrogen Production Process using Renewable Energy Sources in a Chemical Plant" aims to address the increasing g...
The project titled "Design and Optimization of a Sustainable Process for Biodiesel Production from Waste Cooking Oil" aims to address the significant ...
The project titled "Optimization of Chemical Reactor Design for Sustainable Production Processes" aims to address the critical need for sustainable pr...
The research project, titled "Optimization of Bioreactor Design for Enhanced Production of Biofuels," aims to address the growing demand for sustainab...
The project titled "Optimization of Biogas Production from Food Waste through Anaerobic Digestion" aims to address the pressing need for sustainable w...
The project titled "Design and Optimization of a Chemical Process for Renewable Energy Production" aims to address the growing global demand for susta...