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Phytochemical analysis and the anti-inflammatory activities of dichloromethane fraction of methhanol extract of crateva adansonii

 

Table Of Contents


Chapter ONE

1.1 Introduction
1.2 Background of Study
1.3 Problem Statement
1.4 Objective of Study
1.5 Limitation of Study
1.6 Scope of Study
1.7 Significance of Study
1.8 Structure of the Research
1.9 Definition of Terms

Chapter TWO

2.1 Introduction to Literature Review
2.2 Overview of Phytochemical Analysis
2.3 Anti-Inflammatory Activities of Phytochemicals
2.4 Previous Studies on Crateva Adansonii
2.5 Dichloromethane Fraction Extraction Methods
2.6 Methanol Extract Preparation
2.7 Phytochemical Analysis Techniques
2.8 Anti-Inflammatory Assays
2.9 Mechanisms of Anti-Inflammatory Actions
2.10 Summary of Literature Review

Chapter THREE

3.1 Introduction to Research Methodology
3.2 Research Design
3.3 Sampling Techniques
3.4 Data Collection Methods
3.5 Data Analysis Procedures
3.6 Experimental Setup
3.7 Statistical Analysis
3.8 Ethical Considerations

Chapter FOUR

4.1 Introduction to Discussion of Findings
4.2 Phytochemical Analysis Results
4.3 Anti-Inflammatory Activities Findings
4.4 Comparison with Previous Studies
4.5 Interpretation of Results
4.6 Implications of Findings
4.7 Recommendations for Further Research
4.8 Conclusion of Findings Discussion

Chapter FIVE

5.1 Conclusion and Summary of the Project Research

Thesis Abstract

Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants (Ryan & Majno, 1983). The urgency generated by increased rate of stroke, atherosclerosis attribute due to prolonged use of cyclooxygenase-1 and Cyclooxygenase- 2 inhibitors have accelerated anti-inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate research (Ryan & Majno, 1983). Attention increasingly has been directed to natural products. These are often more affordable and available and sometimes are perceived as more effective than conventional anti- inflammatory drugs.
Anti-inflammation was carried out using 12 rats which was divided into three groups of 4 rats each. Group 1 and 2 served as the negative and positive control respectively. Group 3 received 25mg/kg b.w. of the dichloromethane fraction of methanol extract of Crateva adansonii showed significance anti-inflammatory activity when compared with the standard difference used.

Thesis Overview

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