Thesis Abstract

Abstract
In recent years, nanotechnology has emerged as a promising field with vast potential for revolutionizing drug delivery systems, particularly in the context of targeted cancer therapy. This thesis aims to investigate the application of nanotechnology in enhancing drug delivery systems for targeted cancer therapy, with a focus on improving treatment efficacy and minimizing adverse effects. The use of nanocarriers, such as nanoparticles, liposomes, and micelles, offers unique advantages in delivering therapeutic agents specifically to cancer cells while sparing healthy tissues. The introduction provides an overview of the research problem and sets the stage for the study. The background of the study delves into the principles of nanotechnology and its applications in medicine, highlighting its potential to transform cancer treatment. The problem statement emphasizes the challenges in current cancer therapies and the need for more effective and targeted delivery systems. The objectives of the study outline the specific goals and research questions that will be addressed. The literature review critically analyzes existing research on nanotechnology-based drug delivery systems for cancer therapy. Ten key areas are explored, including the types of nanocarriers, strategies for targeting cancer cells, mechanisms of drug release, and the role of nanotechnology in overcoming multidrug resistance. The research methodology section details the experimental approach and methods used in this study. Eight components are discussed, including the selection of nanocarriers, drug loading techniques, in vitro and in vivo evaluation methods, and data analysis procedures. The chapter provides a comprehensive overview of the research design and methodology employed to investigate the potential use of nanotechnology in enhancing drug delivery systems for targeted cancer therapy. The discussion of findings chapter presents the results of the study, highlighting the effectiveness of nanotechnology in improving drug delivery to cancer cells and enhancing therapeutic outcomes. Various factors influencing the performance of nanocarriers, such as size, surface properties, and release kinetics, are analyzed in detail. The chapter also discusses the implications of the findings for future research and clinical applications. In conclusion, this thesis underscores the significant potential of nanotechnology in advancing drug delivery systems for targeted cancer therapy. The integration of nanocarriers offers a promising avenue for enhancing treatment efficacy, reducing side effects, and overcoming drug resistance in cancer treatment. By optimizing the design and properties of nanocarriers, personalized and precise cancer therapy can be achieved, leading to improved patient outcomes and quality of life. Keywords Nanotechnology, Drug Delivery Systems, Cancer Therapy, Nanocarriers, Targeted Drug Delivery, Nanoparticles, Liposomes, Micelles, Therapeutic Agents, Treatment Efficacy.

Thesis Overview

The project titled "Investigating the potential use of nanotechnology in enhancing drug delivery systems for targeted cancer therapy" aims to explore the application of nanotechnology in revolutionizing drug delivery systems for more effective and precise treatment of cancer. Cancer remains a significant health challenge globally, with conventional chemotherapy often associated with severe side effects due to non-specific targeting of healthy cells alongside cancerous ones. Nanotechnology offers a promising solution by enabling the design of nanoscale drug delivery systems that can specifically target cancer cells while minimizing damage to healthy tissues. This research will begin with a comprehensive literature review to examine existing studies and advancements in the field of nanotechnology and cancer therapy. By investigating the various types of nanoparticles, drug encapsulation techniques, targeting strategies, and delivery mechanisms, the project aims to identify key trends and gaps in the current research landscape. The literature review will also explore the challenges and opportunities in the application of nanotechnology for targeted cancer therapy. Moving forward, the research methodology will involve experimental investigations to evaluate the effectiveness of different nanotechnology-based drug delivery systems in targeting cancer cells. Through in vitro and potentially in vivo studies, the project will assess parameters such as drug release kinetics, cellular uptake, cytotoxicity, and therapeutic efficacy of the developed nanocarriers. The research will also explore the potential synergistic effects of combining nanotechnology with traditional cancer treatments to enhance therapeutic outcomes. The findings from the experimental studies will be critically analyzed and discussed in detail in the subsequent chapters. The discussion will focus on the implications of the results in advancing the field of targeted cancer therapy using nanotechnology. By elucidating the mechanisms of action, limitations, and future directions of nanotechnology-based drug delivery systems, the research aims to contribute valuable insights to the scientific community and pharmaceutical industry. In conclusion, this project seeks to shed light on the transformative potential of nanotechnology in enhancing drug delivery systems for targeted cancer therapy. By leveraging the unique properties of nanoparticles to improve drug stability, circulation time, and tumor specificity, nanotechnology holds great promise for personalized and precision medicine in the fight against cancer. Through rigorous investigation and analysis, this research endeavor aspires to pave the way for innovative therapeutic strategies that can offer improved outcomes and quality of life for cancer patients.