Thesis Abstract

Abstract
Nanotechnology has emerged as a promising field in the development of innovative approaches for targeted drug delivery in cancer treatment. This thesis investigates the application of nanotechnology in delivering therapeutic agents specifically to cancer cells, aiming to enhance treatment efficacy while minimizing off-target effects. The study explores various nanoscale drug delivery systems, including nanoparticles, liposomes, and micelles, and their potential advantages in improving drug pharmacokinetics and bioavailability. Chapter 1 provides a comprehensive introduction to the research topic, outlining the background of the study, defining the problem statement, setting the objectives, discussing the limitations and scope of the study, emphasizing the significance of the research, and presenting the structure of the thesis along with the definition of key terms. Chapter 2 presents a detailed literature review covering ten key aspects of nanotechnology in targeted drug delivery for cancer treatment. The review synthesizes existing research and knowledge, highlighting the latest advancements, challenges, and opportunities in the field. Chapter 3 focuses on the research methodology employed in this study. It includes discussions on the research design, data collection methods, sample selection criteria, experimental procedures, data analysis techniques, and ethical considerations. The chapter also details the validation and reliability measures taken to ensure the credibility of the research findings. Chapter 4 presents an in-depth discussion of the research findings, analyzing the effectiveness of various nanotechnology-based drug delivery systems in targeting cancer cells. The chapter discusses the outcomes of experimental studies, highlights key observations, and interprets the results in the context of existing literature. Chapter 5 concludes the thesis by summarizing the key findings, discussing their implications for cancer treatment, and providing recommendations for future research directions. The chapter also reflects on the significance of the study in advancing the field of nanotechnology-based drug delivery for cancer therapy. In conclusion, this thesis contributes to the growing body of knowledge on the application of nanotechnology in targeted drug delivery for cancer treatment. The findings underscore the potential of nanoscale drug delivery systems in improving treatment outcomes and reducing side effects, paving the way for the development of more efficient and personalized cancer therapies.

Thesis Overview

The project titled "Investigating the use of nanotechnology in targeted drug delivery for cancer treatment" aims to explore the potential of nanotechnology in enhancing the effectiveness of drug delivery for cancer treatment. Cancer remains a significant global health challenge, with traditional treatments often causing adverse side effects due to their non-specific targeting of healthy cells along with cancerous ones. Nanotechnology offers a promising solution by enabling the precise delivery of therapeutic agents directly to cancer cells, thereby minimizing collateral damage to healthy tissues. This research will delve into the background of nanotechnology and its application in medicine, particularly in the field of oncology. The study will identify the existing challenges in cancer treatment, such as drug resistance and systemic toxicity, and how nanotechnology can address these issues through targeted drug delivery systems. By encapsulating anticancer drugs within nanoparticles, researchers can improve drug solubility, stability, and bioavailability while also enabling controlled release at the tumor site. The project will focus on elucidating the mechanisms by which nanocarriers navigate the complex biological barriers to reach the tumor site effectively. Understanding the interactions between nanoparticles and biological systems is crucial for optimizing drug delivery efficiency and therapeutic outcomes. Additionally, the research will explore the role of surface functionalization in enhancing the specificity of nanocarriers for cancer cells, thereby increasing treatment efficacy and reducing off-target effects. Furthermore, this study will investigate the various types of nanocarriers, such as liposomes, polymeric nanoparticles, dendrimers, and carbon-based nanomaterials, and their specific applications in targeted drug delivery for different types of cancers. By comparing the advantages and limitations of these nanocarriers, the research aims to provide insights into selecting the most suitable delivery system based on the unique characteristics of the cancer type and patient profile. Moreover, the project will evaluate the preclinical and clinical studies that have demonstrated the potential of nanotechnology-based drug delivery systems in improving cancer treatment outcomes. By analyzing the current state of research and development in this field, the study aims to identify gaps in knowledge and propose future directions for advancing nanotechnology in cancer therapy. In conclusion, this research project seeks to contribute to the growing body of knowledge on the application of nanotechnology in targeted drug delivery for cancer treatment. By investigating the mechanisms, challenges, and opportunities associated with nanocarrier-based therapies, the study aims to pave the way for more effective and personalized cancer treatments that minimize side effects and improve patient outcomes.