"The Role of Genetics in Predisposition to Certain Diseases."
Table Of Contents
<p>1. Introduction<br> 1.1 Background<br> 1.2 Research Objectives<br> 1.3 Significance of the Study<br><br>2. Genetic Basis of Disease Predisposition<br> 2.1 Overview of Genetics and Inheritance<br> 2.2 Genetic Disorders: Mendelian Inheritance Patterns<br> 2.3 Complex Multifactorial Diseases: Polygenic Inheritance<br><br>3. Identifying Disease-Associated Genes<br> 3.1 Genome-Wide Association Studies (GWAS)<br> 3.2 Candidate Gene Approach<br> 3.3 Functional Genomics and Gene Expression Studies<br><br>4. Genetic Markers and Disease Risk<br> 4.1 Single Nucleotide Polymorphisms (SNPs)<br> 4.2 Copy Number Variations (CNVs)<br> 4.3 Microsatellites and Tandem Repeats<br><br>5. Gene-Environment Interactions<br> 5.1 Environmental Factors Influencing Disease Risk<br> 5.2 Gene-Environment Interplay<br> 5.3 Epigenetics and Disease Susceptibility<br></p>
Thesis Abstract
<p> This research project aims to explore the role of genetics in determining an individual's susceptibility to certain diseases. It investigates how variations in genetic makeup can influence the likelihood of developing specific diseases, including both genetic disorders and complex multifactorial diseases. The project will delve into the underlying mechanisms of genetic predisposition, including the identification of specific genes and genetic markers associated with increased disease risk. Additionally, it will examine the impact of environmental factors and gene-environment interactions on disease susceptibility. The findings of this study will contribute to a better understanding of the genetic basis of diseases and may have implications for personalized medicine and disease prevention strategies. <br></p>Thesis Overview
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